GSM5528727

Dataset: gse182409 • Sample: T231 • Status: Pregnancy-stage cohort
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Quality Control Metrics

62,592,240 Total counts Group median: 70,855,220 • 27.1%ile (≈ Median)
32,490 Detected genes Group median: 31,576 • 72.3%ile (≈ Median)
0 Mitochondrial fraction (%) Group median: 0 • 89.4%ile (↑ High)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

54.3Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.61
bar=donor   line=cohort median 		9.31 74.1%
CETP Lipid Metabolism 2.24
bar=donor   line=cohort median 		1.18 94.1%
SIRT6 Sirtuin Family 2.27
bar=donor   line=cohort median 		2.22 58.3%
SIRT1 Sirtuin Family 5.36
bar=donor   line=cohort median 		5.50 16.9%
SIRT3 Sirtuin Family 2.60
bar=donor   line=cohort median 		2.33 86.6%
IGF1R Insulin/IGF-1 Signaling 6.63
bar=donor   line=cohort median 		7.09 10.7%
KLOTHO Anti-aging 0.15
bar=donor   line=cohort median 		0.66 19.0%
IRS2 Insulin/IGF-1 Signaling 5.26
bar=donor   line=cohort median 		5.59 24.5%
TP53 Tumor Suppression 3.55
bar=donor   line=cohort median 		2.72 91.4%
SHC1 Signal Transduction 4.06
bar=donor   line=cohort median 		3.95 67.2%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 14.9 1,636,402
2 ENSG00000258486 ENSG00000258486 14.9 1,399,289
3 7SK ENSG00000202198 misc_RNA 14.5 1,171,851
4 MALAT1 ENSG00000251562 lncRNA 13.9 603,192
5 AL355075.4 ENSG00000259001 lncRNA 13.2 415,568
6 B2M ENSG00000166710 protein_coding 13.0 467,450
7 S100A9 ENSG00000163220 protein_coding 12.9 359,641
8 EEF1A1 ENSG00000156508 protein_coding 12.4 235,304
9 BNIP3L ENSG00000104765 protein_coding 12.3 220,169
10 NAMPT ENSG00000105835 protein_coding 12.1 224,212

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.7
bar=donor   line=cohort median 		11.8 11.8 43.5%
2 S100A9 protein_coding 12.9
bar=donor   line=cohort median 		13.1 13.1 33.2%
3 IL1B protein_coding 6.1
bar=donor   line=cohort median 		6.9 6.9 10.6%
4 CXCL8 protein_coding 6.1
bar=donor   line=cohort median 		7.6 7.6 12.0%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 3.2
bar=donor   line=cohort median 		4.0 4.0 25.7%
6 FCGR3B protein_coding 10.9
bar=donor   line=cohort median 		11.3 11.3 19.5%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 10.7
bar=donor   line=cohort median 		10.9 10.9 30.5%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.7
bar=donor   line=cohort median 		5.3 5.3 85.3%
9 CD3E protein_coding 3.5
bar=donor   line=cohort median 		2.6 2.6 90.1%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 7.2
bar=donor   line=cohort median 		6.3 6.3 96.9%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 3.1
bar=donor   line=cohort median 		3.4 3.4 33.9%
12 GNLY protein_coding 5.3
bar=donor   line=cohort median 		4.9 4.9 73.6%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 5.6
bar=donor   line=cohort median 		6.6 6.6 26.4%
14 HBA1 protein_coding -0.4
bar=donor   line=cohort median 		2.6 2.6 14.0%
15 HBA2 protein_coding 2.7
bar=donor   line=cohort median 		5.6 5.6 12.0%
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