GSM5528729

Dataset: gse182409 • Sample: T233 • Status: Pregnancy-stage cohort
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Quality Control Metrics

70,892,994 Total counts Group median: 70,855,220 • 50.3%ile (≈ Median)
29,887 Detected genes Group median: 31,576 • 35.3%ile (≈ Median)
0 Mitochondrial fraction (%) Group median: 0 • 21.6%ile (↓ Low)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

39.7Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 8.97
bar=donor   line=cohort median 		9.31 22.4%
CETP Lipid Metabolism 1.34
bar=donor   line=cohort median 		1.18 61.7%
SIRT6 Sirtuin Family 1.82
bar=donor   line=cohort median 		2.22 7.9%
SIRT1 Sirtuin Family 5.50
bar=donor   line=cohort median 		5.50 49.3%
SIRT3 Sirtuin Family 2.39
bar=donor   line=cohort median 		2.33 59.7%
IGF1R Insulin/IGF-1 Signaling 6.92
bar=donor   line=cohort median 		7.09 35.5%
KLOTHO Anti-aging 0.27
bar=donor   line=cohort median 		0.66 21.0%
IRS2 Insulin/IGF-1 Signaling 5.48
bar=donor   line=cohort median 		5.59 37.6%
TP53 Tumor Suppression 2.96
bar=donor   line=cohort median 		2.72 65.9%
SHC1 Signal Transduction 3.85
bar=donor   line=cohort median 		3.95 35.5%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 15.1 1,276,331
2 ENSG00000258486 ENSG00000258486 15.0 1,051,899
3 7SK ENSG00000202198 misc_RNA 14.3 1,005,267
4 MALAT1 ENSG00000251562 lncRNA 13.4 884,358
5 S100A9 ENSG00000163220 protein_coding 13.3 705,443
6 ALAS2 ENSG00000158578 protein_coding 13.3 538,954
7 AL355075.4 ENSG00000259001 lncRNA 13.0 479,868
8 B2M ENSG00000166710 protein_coding 13.0 657,135
9 NAMPT ENSG00000105835 protein_coding 12.5 343,134
10 SLC25A37 ENSG00000147454 protein_coding 12.4 236,468

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 12.0
bar=donor   line=cohort median 		11.8 11.8 66.1%
2 S100A9 protein_coding 13.3
bar=donor   line=cohort median 		13.1 13.1 72.9%
3 IL1B protein_coding 7.0
bar=donor   line=cohort median 		6.9 6.9 60.6%
4 CXCL8 protein_coding 5.8
bar=donor   line=cohort median 		7.6 7.6 8.6%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 5.2
bar=donor   line=cohort median 		4.0 4.0 81.2%
6 FCGR3B protein_coding 11.3
bar=donor   line=cohort median 		11.3 11.3 49.0%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 11.2
bar=donor   line=cohort median 		10.9 10.9 78.4%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 4.9
bar=donor   line=cohort median 		5.3 5.3 11.3%
9 CD3E protein_coding 2.9
bar=donor   line=cohort median 		2.6 2.6 60.6%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 6.5
bar=donor   line=cohort median 		6.3 6.3 68.8%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 3.5
bar=donor   line=cohort median 		3.4 3.4 53.8%
12 GNLY protein_coding 5.2
bar=donor   line=cohort median 		4.9 4.9 68.2%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 9.0
bar=donor   line=cohort median 		6.6 6.6 77.7%
14 HBA1 protein_coding 4.6
bar=donor   line=cohort median 		2.6 2.6 72.3%
15 HBA2 protein_coding 8.7
bar=donor   line=cohort median 		5.6 5.6 82.5%
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