GSM5528731

Dataset: gse182409 • Sample: T235 • Status: Pregnancy-stage cohort
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Quality Control Metrics

72,282,055 Total counts Group median: 70,855,220 • 55.1%ile (≈ Median)
28,604 Detected genes Group median: 31,576 • 19.5%ile (↓ Low)
0 Mitochondrial fraction (%) Group median: 0 • 83.2%ile (↑ High)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

64.1Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.74
bar=donor   line=cohort median 		9.31 82.4%
CETP Lipid Metabolism 0.93
bar=donor   line=cohort median 		1.18 32.1%
SIRT6 Sirtuin Family 2.48
bar=donor   line=cohort median 		2.22 84.5%
SIRT1 Sirtuin Family 5.09
bar=donor   line=cohort median 		5.50 1.7%
SIRT3 Sirtuin Family 2.23
bar=donor   line=cohort median 		2.33 32.8%
IGF1R Insulin/IGF-1 Signaling 7.55
bar=donor   line=cohort median 		7.09 92.1%
KLOTHO Anti-aging 1.42
bar=donor   line=cohort median 		0.66 93.5%
IRS2 Insulin/IGF-1 Signaling 5.90
bar=donor   line=cohort median 		5.59 80.3%
TP53 Tumor Suppression 3.03
bar=donor   line=cohort median 		2.72 71.4%
SHC1 Signal Transduction 4.08
bar=donor   line=cohort median 		3.95 70.0%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 7SK ENSG00000202198 misc_RNA 14.2 903,550
2 ENSG00000258486 ENSG00000258486 14.1 857,688
3 ENSG00000265150 ENSG00000265150 14.0 866,643
4 MALAT1 ENSG00000251562 lncRNA 13.5 715,606
5 ALAS2 ENSG00000158578 protein_coding 13.4 655,095
6 B2M ENSG00000166710 protein_coding 13.3 583,331
7 BNIP3L ENSG00000104765 protein_coding 13.0 399,139
8 AL355075.4 ENSG00000259001 lncRNA 12.8 332,029
9 S100A9 ENSG00000163220 protein_coding 12.6 380,249
10 SLC25A37 ENSG00000147454 protein_coding 12.6 584,672

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.5
bar=donor   line=cohort median 		11.8 11.8 31.2%
2 S100A9 protein_coding 12.6
bar=donor   line=cohort median 		13.1 13.1 14.7%
3 IL1B protein_coding 6.5
bar=donor   line=cohort median 		6.9 6.9 27.1%
4 CXCL8 protein_coding 6.2
bar=donor   line=cohort median 		7.6 7.6 12.7%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 3.6
bar=donor   line=cohort median 		4.0 4.0 38.7%
6 FCGR3B protein_coding 10.8
bar=donor   line=cohort median 		11.3 11.3 16.1%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 11.2
bar=donor   line=cohort median 		10.9 10.9 70.2%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.5
bar=donor   line=cohort median 		5.3 5.3 68.8%
9 CD3E protein_coding 2.7
bar=donor   line=cohort median 		2.6 2.6 51.7%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 5.9
bar=donor   line=cohort median 		6.3 6.3 25.7%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 3.6
bar=donor   line=cohort median 		3.4 3.4 56.5%
12 GNLY protein_coding 5.1
bar=donor   line=cohort median 		4.9 4.9 66.1%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 10.9
bar=donor   line=cohort median 		6.6 6.6 91.4%
14 HBA1 protein_coding 8.2
bar=donor   line=cohort median 		2.6 2.6 99.7%
15 HBA2 protein_coding 11.3
bar=donor   line=cohort median 		5.6 5.6 96.2%
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