GSM5528732

Dataset: gse182409 • Sample: T236 • Status: Pregnancy-stage cohort
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Quality Control Metrics

59,263,206 Total counts Group median: 70,855,220 • 22.3%ile (↓ Low)
29,535 Detected genes Group median: 31,576 • 31.8%ile (≈ Median)
0 Mitochondrial fraction (%) Group median: 0 • 62.7%ile (≈ Median)

GSE182409 values are from the Chinese-only whole-blood raw count matrix and TMM-normalized logCPM matrix.

Longevity Gene Set (15)

53.5Longevity Score (mean cohort rank, 10/15 genes)
GenePathwayExpression (TMM-logCPM)vs CohortCohort Median%ile
FOXO3 Insulin/IGF-1 Signaling 9.57
bar=donor   line=cohort median 		9.31 70.0%
CETP Lipid Metabolism 1.76
bar=donor   line=cohort median 		1.18 83.1%
SIRT6 Sirtuin Family 2.18
bar=donor   line=cohort median 		2.22 46.6%
SIRT1 Sirtuin Family 5.20
bar=donor   line=cohort median 		5.50 2.4%
SIRT3 Sirtuin Family 2.58
bar=donor   line=cohort median 		2.33 83.8%
IGF1R Insulin/IGF-1 Signaling 6.89
bar=donor   line=cohort median 		7.09 30.7%
KLOTHO Anti-aging 0.72
bar=donor   line=cohort median 		0.66 56.2%
IRS2 Insulin/IGF-1 Signaling 5.85
bar=donor   line=cohort median 		5.59 72.8%
TP53 Tumor Suppression 2.65
bar=donor   line=cohort median 		2.72 45.2%
SHC1 Signal Transduction 3.88
bar=donor   line=cohort median 		3.95 43.8%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (logCPM)Count
1 ENSG00000265150 ENSG00000265150 14.2 697,740
2 ENSG00000258486 ENSG00000258486 14.0 734,550
3 7SK ENSG00000202198 misc_RNA 13.7 788,500
4 MALAT1 ENSG00000251562 lncRNA 13.5 485,922
5 ALAS2 ENSG00000158578 protein_coding 12.8 447,872
6 B2M ENSG00000166710 protein_coding 12.6 416,704
7 S100A9 ENSG00000163220 protein_coding 12.6 261,605
8 SLC25A37 ENSG00000147454 protein_coding 12.4 256,738
9 EPB41 ENSG00000159023 protein_coding 12.2 226,260
10 BNIP3L ENSG00000104765 protein_coding 12.0 356,034

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 11.4
bar=donor   line=cohort median 		11.8 11.8 20.2%
2 S100A9 protein_coding 12.6
bar=donor   line=cohort median 		13.1 13.1 13.4%
3 IL1B protein_coding 6.6
bar=donor   line=cohort median 		6.9 6.9 31.8%
4 CXCL8 protein_coding 5.4
bar=donor   line=cohort median 		7.6 7.6 3.8%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 5.3
bar=donor   line=cohort median 		4.0 4.0 85.3%
6 FCGR3B protein_coding 10.9
bar=donor   line=cohort median 		11.3 11.3 18.2%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 10.9
bar=donor   line=cohort median 		10.9 10.9 53.1%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 5.0
bar=donor   line=cohort median 		5.3 5.3 19.5%
9 CD3E protein_coding 4.0
bar=donor   line=cohort median 		2.6 2.6 96.9%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 7.0
bar=donor   line=cohort median 		6.3 6.3 94.2%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 4.7
bar=donor   line=cohort median 		3.4 3.4 95.5%
12 GNLY protein_coding 4.7
bar=donor   line=cohort median 		4.9 4.9 39.4%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 8.1
bar=donor   line=cohort median 		6.6 6.6 70.2%
14 HBA1 protein_coding 6.6
bar=donor   line=cohort median 		2.6 2.6 88.0%
15 HBA2 protein_coding 9.4
bar=donor   line=cohort median 		5.6 5.6 86.6%
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