GSM6881282

Dataset: gse221521 • Sample: Control group RNA318 • Status: Healthy control
◂ Prev All Donors Next ▸

Quality Control Metrics

12,244,699 Total counts Group median: 12,762,148 • 35.5%ile (≈ Median)
27,838 Detected genes Group median: 2,606 • 85.2%ile (↑ High)
8 Mitochondrial fraction (%) Group median: 6 • 83.7%ile (↑ High)

FPKM/count values are derived from the public processed GSE221521 expression matrix.

Longevity Gene Set (15)

52.4Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (FPKM)vs CohortCohort Median%ile
APOE Lipid Metabolism 0.41
bar=donor   line=cohort median 		0.17 95.6%
FOXO3 Insulin/IGF-1 Signaling 10.12
bar=donor   line=cohort median 		12.92 22.0%
CETP Lipid Metabolism 0.40
bar=donor   line=cohort median 		0.40 51.6%
SIRT6 Sirtuin Family 3.17
bar=donor   line=cohort median 		3.67 23.1%
SIRT1 Sirtuin Family 3.69
bar=donor   line=cohort median 		3.48 62.4%
SIRT3 Sirtuin Family 1.66
bar=donor   line=cohort median 		1.10 97.2%
IGF1R Insulin/IGF-1 Signaling 2.36
bar=donor   line=cohort median 		4.33 23.6%
KLOTHO Anti-aging 0.00
bar=donor   line=cohort median 		0.06 5.2%
APOC3 Lipid Metabolism 0.00
bar=donor   line=cohort median 		0.00 48.5%
IL6 Inflammation 0.10
bar=donor   line=cohort median 		0.07 68.7%
TERT Telomere Maintenance 0.00
bar=donor   line=cohort median 		0.01 18.7%
IRS2 Insulin/IGF-1 Signaling 18.85
bar=donor   line=cohort median 		35.28 15.3%
TP53 Tumor Suppression 4.85
bar=donor   line=cohort median 		3.83 74.9%
SHC1 Signal Transduction 9.64
bar=donor   line=cohort median 		8.77 80.1%
ACE Signal Transduction 1.49
bar=donor   line=cohort median 		0.39 98.7%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (FPKM)Count
1 MT-RNR2 ENSG00000210082 Mt_rRNA 11,671.2 222,797
2 MT-CO2 ENSG00000198712 protein_coding 9,322.1 78,076
3 MT-CO1 ENSG00000198804 protein_coding 8,240.5 155,591
4 MT-RNR1 ENSG00000211459 Mt_rRNA 7,443.0 86,945
5 MT-CO3 ENSG00000198938 protein_coding 7,047.1 67,651
6 S100A9 ENSG00000163220 protein_coding 5,761.5 40,424
7 MT-ND3 ENSG00000198840 protein_coding 5,495.1 23,281
8 AC005912.1 ENSG00000227081 processed_pseudogene 5,466.0 17,067
9 MT-ND1 ENSG00000198888 protein_coding 5,209.0 60,976
10 MT-ND2 ENSG00000198763 protein_coding 4,976.4 63,494

Immune Marker Gene Expression (18 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 1,152.9
bar=donor   line=cohort median 		1,535.8 1,385.4 33.9%
2 S100A9 protein_coding 5,761.5
bar=donor   line=cohort median 		10,851.3 9,235.1 17.9%
3 IL1B protein_coding 4.3
bar=donor   line=cohort median 		5.6 6.1 29.3%
4 CXCL8 protein_coding 100.1
bar=donor   line=cohort median 		220.4 207.4 19.9%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 1.1
bar=donor   line=cohort median 		1.7 2.4 18.9%
6 FCGR3B protein_coding 31.5
bar=donor   line=cohort median 		145.0 129.3 8.5%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 349.9
bar=donor   line=cohort median 		709.1 706.2 15.3%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 88.1
bar=donor   line=cohort median 		66.1 56.4 82.1%
9 CD3E protein_coding 56.5
bar=donor   line=cohort median 		37.6 37.7 84.7%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 3.9
bar=donor   line=cohort median 		3.1 3.1 66.6%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 525.7
bar=donor   line=cohort median 		302.3 281.6 89.4%
12 GNLY protein_coding 171.8
bar=donor   line=cohort median 		80.1 70.7 94.0%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 929.7
bar=donor   line=cohort median 		598.7 582.1 69.2%
14 HBA1 protein_coding 3,818.5
bar=donor   line=cohort median 		2,133.6 1,960.7 72.3%
15 HBA2 protein_coding 2,040.0
bar=donor   line=cohort median 		1,142.2 1,083.5 70.7%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 protein_coding 8,240.5
bar=donor   line=cohort median 		6,862.1 6,938.4 71.8%
17 MT-CO2 protein_coding 9,322.1
bar=donor   line=cohort median 		6,023.6 5,810.8 87.8%
18 MT-ND1 protein_coding 5,209.0
bar=donor   line=cohort median 		3,656.3 3,718.2 82.1%
◂ Previous Donor Back to Donor List Next Donor ▸