GSM6881295

Dataset: gse221521 • Sample: Control group RNA339 • Status: Healthy control
◂ Prev All Donors Next ▸

Quality Control Metrics

12,845,906 Total counts Group median: 12,762,148 • 59.3%ile (≈ Median)
26,493 Detected genes Group median: 2,606 • 51.6%ile (≈ Median)
8 Mitochondrial fraction (%) Group median: 6 • 85.2%ile (↑ High)

FPKM/count values are derived from the public processed GSE221521 expression matrix.

Longevity Gene Set (15)

56.8Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (FPKM)vs CohortCohort Median%ile
APOE Lipid Metabolism 0.29
bar=donor   line=cohort median 		0.17 79.5%
FOXO3 Insulin/IGF-1 Signaling 7.30
bar=donor   line=cohort median 		12.92 10.1%
CETP Lipid Metabolism 0.88
bar=donor   line=cohort median 		0.40 95.1%
SIRT6 Sirtuin Family 4.84
bar=donor   line=cohort median 		3.67 89.9%
SIRT1 Sirtuin Family 3.37
bar=donor   line=cohort median 		3.48 41.2%
SIRT3 Sirtuin Family 1.29
bar=donor   line=cohort median 		1.10 76.9%
IGF1R Insulin/IGF-1 Signaling 2.10
bar=donor   line=cohort median 		4.33 18.9%
KLOTHO Anti-aging 0.01
bar=donor   line=cohort median 		0.06 14.3%
APOC3 Lipid Metabolism 0.00
bar=donor   line=cohort median 		0.00 48.5%
IL6 Inflammation 0.13
bar=donor   line=cohort median 		0.07 80.1%
TERT Telomere Maintenance 0.01
bar=donor   line=cohort median 		0.01 43.3%
IRS2 Insulin/IGF-1 Signaling 6.48
bar=donor   line=cohort median 		35.28 2.3%
TP53 Tumor Suppression 5.48
bar=donor   line=cohort median 		3.83 85.8%
SHC1 Signal Transduction 9.50
bar=donor   line=cohort median 		8.77 74.9%
ACE Signal Transduction 0.80
bar=donor   line=cohort median 		0.39 90.9%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (FPKM)Count
1 MT-RNR2 ENSG00000210082 Mt_rRNA 11,295.6 226,215
2 HBA1 ENSG00000206172 protein_coding 10,429.9 230,449
3 MT-CO1 ENSG00000198804 protein_coding 9,950.9 197,111
4 MT-CO2 ENSG00000198712 protein_coding 9,165.8 80,536
5 MT-CO3 ENSG00000198938 protein_coding 9,030.0 90,943
6 RPS28P7 ENSG00000227097 processed_pseudogene 6,796.7 18,335
7 MT-ND3 ENSG00000198840 protein_coding 5,920.1 26,313
8 MT-RNR1 ENSG00000211459 Mt_rRNA 5,861.6 71,834
9 MT-ND4 ENSG00000198886 protein_coding 5,387.8 95,373
10 MT-ND1 ENSG00000198888 protein_coding 5,385.5 66,138

Immune Marker Gene Expression (18 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 369.6
bar=donor   line=cohort median 		1,535.8 1,385.4 2.8%
2 S100A9 protein_coding 1,954.0
bar=donor   line=cohort median 		10,851.3 9,235.1 2.8%
3 IL1B protein_coding 0.8
bar=donor   line=cohort median 		5.6 6.1 5.4%
4 CXCL8 protein_coding 45.6
bar=donor   line=cohort median 		220.4 207.4 8.0%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 2.7
bar=donor   line=cohort median 		1.7 2.4 57.8%
6 FCGR3B protein_coding 16.5
bar=donor   line=cohort median 		145.0 129.3 3.4%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 318.2
bar=donor   line=cohort median 		709.1 706.2 12.7%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 149.8
bar=donor   line=cohort median 		66.1 56.4 98.2%
9 CD3E protein_coding 100.5
bar=donor   line=cohort median 		37.6 37.7 99.2%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 3.7
bar=donor   line=cohort median 		3.1 3.1 64.5%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 619.9
bar=donor   line=cohort median 		302.3 281.6 95.1%
12 GNLY protein_coding 199.6
bar=donor   line=cohort median 		80.1 70.7 96.6%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 2,408.4
bar=donor   line=cohort median 		598.7 582.1 94.0%
14 HBA1 protein_coding 10,429.9
bar=donor   line=cohort median 		2,133.6 1,960.7 94.6%
15 HBA2 protein_coding 5,083.7
bar=donor   line=cohort median 		1,142.2 1,083.5 92.0%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 protein_coding 9,950.9
bar=donor   line=cohort median 		6,862.1 6,938.4 92.0%
17 MT-CO2 protein_coding 9,165.8
bar=donor   line=cohort median 		6,023.6 5,810.8 86.8%
18 MT-ND1 protein_coding 5,385.5
bar=donor   line=cohort median 		3,656.3 3,718.2 83.2%
◂ Previous Donor Back to Donor List Next Donor ▸