GSM6881327

Dataset: gse221521 • Sample: Control group RNA449 • Status: Healthy control
◂ Prev All Donors Next ▸

Quality Control Metrics

13,141,108 Total counts Group median: 12,762,148 • 68.1%ile (≈ Median)
26,401 Detected genes Group median: 2,606 • 47.4%ile (≈ Median)
9 Mitochondrial fraction (%) Group median: 6 • 88.9%ile (↑ High)

FPKM/count values are derived from the public processed GSE221521 expression matrix.

Longevity Gene Set (15)

50.8Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (FPKM)vs CohortCohort Median%ile
APOE Lipid Metabolism 0.08
bar=donor   line=cohort median 		0.17 23.1%
FOXO3 Insulin/IGF-1 Signaling 11.82
bar=donor   line=cohort median 		12.92 38.6%
CETP Lipid Metabolism 0.32
bar=donor   line=cohort median 		0.40 33.4%
SIRT6 Sirtuin Family 3.71
bar=donor   line=cohort median 		3.67 51.6%
SIRT1 Sirtuin Family 3.56
bar=donor   line=cohort median 		3.48 56.2%
SIRT3 Sirtuin Family 0.81
bar=donor   line=cohort median 		1.10 10.6%
IGF1R Insulin/IGF-1 Signaling 6.06
bar=donor   line=cohort median 		4.33 79.0%
KLOTHO Anti-aging 0.03
bar=donor   line=cohort median 		0.06 26.7%
APOC3 Lipid Metabolism 0.05
bar=donor   line=cohort median 		0.00 97.2%
IL6 Inflammation 0.43
bar=donor   line=cohort median 		0.07 98.7%
TERT Telomere Maintenance 0.02
bar=donor   line=cohort median 		0.01 67.1%
IRS2 Insulin/IGF-1 Signaling 36.29
bar=donor   line=cohort median 		35.28 52.1%
TP53 Tumor Suppression 3.55
bar=donor   line=cohort median 		3.83 39.6%
SHC1 Signal Transduction 7.50
bar=donor   line=cohort median 		8.77 10.6%
ACE Signal Transduction 0.56
bar=donor   line=cohort median 		0.39 78.0%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (FPKM)Count
1 MT-RNR2 ENSG00000210082 Mt_rRNA 14,486.3 296,781
2 MT-RNR1 ENSG00000211459 Mt_rRNA 10,157.4 127,340
3 MT-CO1 ENSG00000198804 protein_coding 9,389.5 190,264
4 MT-CO3 ENSG00000198938 protein_coding 9,216.5 94,954
5 MT-CO2 ENSG00000198712 protein_coding 8,965.3 80,585
6 S100A9 ENSG00000163220 protein_coding 8,943.9 67,346
7 MT-ND1 ENSG00000198888 protein_coding 6,075.0 76,319
8 MT-ND3 ENSG00000198840 protein_coding 5,494.2 24,981
9 FTL ENSG00000087086 protein_coding 5,346.7 61,198
10 MT-ND4 ENSG00000198886 protein_coding 4,997.4 90,496

Immune Marker Gene Expression (18 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 protein_coding 1,563.0
bar=donor   line=cohort median 		1,535.8 1,385.4 56.2%
2 S100A9 protein_coding 8,943.9
bar=donor   line=cohort median 		10,851.3 9,235.1 47.9%
3 IL1B protein_coding 3.4
bar=donor   line=cohort median 		5.6 6.1 21.0%
4 CXCL8 protein_coding 146.1
bar=donor   line=cohort median 		220.4 207.4 31.3%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO protein_coding 1.1
bar=donor   line=cohort median 		1.7 2.4 19.9%
6 FCGR3B protein_coding 210.5
bar=donor   line=cohort median 		145.0 129.3 80.1%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ protein_coding 737.5
bar=donor   line=cohort median 		709.1 706.2 54.1%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D protein_coding 83.3
bar=donor   line=cohort median 		66.1 56.4 79.0%
9 CD3E protein_coding 46.3
bar=donor   line=cohort median 		37.6 37.7 71.2%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 protein_coding 5.6
bar=donor   line=cohort median 		3.1 3.1 87.8%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 protein_coding 203.6
bar=donor   line=cohort median 		302.3 281.6 25.6%
12 GNLY protein_coding 40.3
bar=donor   line=cohort median 		80.1 70.7 16.8%

Hemoglobin / erythroid (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
13 HBB protein_coding 827.0
bar=donor   line=cohort median 		598.7 582.1 65.5%
14 HBA1 protein_coding 3,534.2
bar=donor   line=cohort median 		2,133.6 1,960.7 69.2%
15 HBA2 protein_coding 2,070.6
bar=donor   line=cohort median 		1,142.2 1,083.5 72.8%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 protein_coding 9,389.5
bar=donor   line=cohort median 		6,862.1 6,938.4 88.3%
17 MT-CO2 protein_coding 8,965.3
bar=donor   line=cohort median 		6,023.6 5,810.8 85.8%
18 MT-ND1 protein_coding 6,075.0
bar=donor   line=cohort median 		3,656.3 3,718.2 88.9%
◂ Previous Donor Back to Donor List Next Donor ▸