GSM8077465

Dataset: gse255685 • Sample: YZ369 • Status: MDD with drug therapy
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Quality Control Metrics

2 Mean expression score Group median: 2 • 31.7%ile (≈ Median)
22,362 Genes with score > 0 Group median: 22,378 • 29.0%ile (≈ Median)
0 Median expression score Group median: 0 • 21.0%ile (↓ Low)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

46.9Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 1.72
bar=donor   line=cohort median 		2.02 4.1%
FOXO3 Insulin/IGF-1 Signaling 9.66
bar=donor   line=cohort median 		9.99 11.7%
CETP Lipid Metabolism 5.55
bar=donor   line=cohort median 		5.05 92.7%
SIRT6 Sirtuin Family 8.43
bar=donor   line=cohort median 		8.34 66.1%
SIRT1 Sirtuin Family 8.82
bar=donor   line=cohort median 		8.72 71.5%
SIRT3 Sirtuin Family 7.59
bar=donor   line=cohort median 		7.49 66.5%
IGF1R Insulin/IGF-1 Signaling 10.18
bar=donor   line=cohort median 		10.21 47.5%
KLOTHO Anti-aging 2.10
bar=donor   line=cohort median 		2.51 2.3%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 65.1%
IL6 Inflammation 1.28
bar=donor   line=cohort median 		1.16 72.6%
TERT Telomere Maintenance 1.39
bar=donor   line=cohort median 		1.51 23.8%
IRS2 Insulin/IGF-1 Signaling 9.36
bar=donor   line=cohort median 		9.81 13.8%
TP53 Tumor Suppression 9.12
bar=donor   line=cohort median 		8.92 81.5%
SHC1 Signal Transduction 9.23
bar=donor   line=cohort median 		9.35 12.7%
ACE Signal Transduction 4.84
bar=donor   line=cohort median 		4.64 71.5%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.8 0
2 B2M 17.1 0
3 EEF1A1 16.7 0
4 ACTB 16.6 0
5 HLA-C 16.4 0
6 MT-CO1 16.4 0
7 HLA-B 16.3 0
8 MT-RNR1 16.3 0
9 S100A9 15.9 0
10 HLA-E 15.9 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 14.7
bar=donor   line=cohort median 		14.2 14.2 83.0%
2 S100A9 15.9
bar=donor   line=cohort median 		15.4 15.5 78.0%
3 IL1B 9.9
bar=donor   line=cohort median 		9.5 9.3 82.3%
4 CXCL8 9.4
bar=donor   line=cohort median 		10.3 11.4 17.7%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 6.2
bar=donor   line=cohort median 		6.1 6.1 59.7%
6 FCGR3B 15.1
bar=donor   line=cohort median 		14.7 14.7 80.5%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.6
bar=donor   line=cohort median 		14.4 14.3 68.6%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.5
bar=donor   line=cohort median 		10.3 10.4 62.5%
9 CD3E 12.1
bar=donor   line=cohort median 		11.9 12.0 65.8%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 11.0
bar=donor   line=cohort median 		10.9 10.9 58.2%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 11.3
bar=donor   line=cohort median 		11.5 11.7 20.6%
12 GNLY 12.0
bar=donor   line=cohort median 		12.0 12.1 41.0%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.4
bar=donor   line=cohort median 		16.4 16.4 47.8%
17 MT-CO2 15.5
bar=donor   line=cohort median 		15.3 15.3 69.4%
18 MT-ND1 15.5
bar=donor   line=cohort median 		15.2 15.2 81.2%
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