GSM8077468

Dataset: gse255685 • Sample: YZ403 • Status: MDD without drug therapy
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Quality Control Metrics

2 Mean expression score Group median: 2 • 27.1%ile (≈ Median)
22,366 Genes with score > 0 Group median: 22,375 • 33.9%ile (≈ Median)
0 Median expression score Group median: 0 • 19.2%ile (↓ Low)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

46.9Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 1.69
bar=donor   line=cohort median 		2.02 0.5%
FOXO3 Insulin/IGF-1 Signaling 9.85
bar=donor   line=cohort median 		9.99 29.2%
CETP Lipid Metabolism 5.09
bar=donor   line=cohort median 		5.05 56.8%
SIRT6 Sirtuin Family 8.19
bar=donor   line=cohort median 		8.34 17.4%
SIRT1 Sirtuin Family 8.87
bar=donor   line=cohort median 		8.72 78.7%
SIRT3 Sirtuin Family 7.73
bar=donor   line=cohort median 		7.49 89.1%
IGF1R Insulin/IGF-1 Signaling 10.25
bar=donor   line=cohort median 		10.21 54.7%
KLOTHO Anti-aging 2.57
bar=donor   line=cohort median 		2.51 59.0%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 17.0%
IL6 Inflammation 1.14
bar=donor   line=cohort median 		1.16 45.7%
TERT Telomere Maintenance 1.62
bar=donor   line=cohort median 		1.51 75.5%
IRS2 Insulin/IGF-1 Signaling 9.45
bar=donor   line=cohort median 		9.81 18.1%
TP53 Tumor Suppression 9.20
bar=donor   line=cohort median 		8.92 92.7%
SHC1 Signal Transduction 9.32
bar=donor   line=cohort median 		9.35 40.3%
ACE Signal Transduction 4.41
bar=donor   line=cohort median 		4.64 28.1%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.4 0
2 B2M 16.8 0
3 EEF1A1 16.6 0
4 ACTB 16.5 0
5 MT-CO1 16.3 0
6 MT-RNR1 15.9 0
7 HLA-C 15.8 0
8 HLA-E 15.6 0
9 HLA-B 15.5 0
10 MT-ND4 15.5 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 13.5
bar=donor   line=cohort median 		13.8 14.2 16.3%
2 S100A9 15.0
bar=donor   line=cohort median 		15.3 15.5 15.2%
3 IL1B 9.3
bar=donor   line=cohort median 		9.5 9.3 48.6%
4 CXCL8 9.9
bar=donor   line=cohort median 		10.6 11.4 26.0%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 6.0
bar=donor   line=cohort median 		6.0 6.1 43.2%
6 FCGR3B 14.5
bar=donor   line=cohort median 		14.6 14.7 31.4%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 13.5
bar=donor   line=cohort median 		14.3 14.3 2.7%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.4
bar=donor   line=cohort median 		10.2 10.4 57.5%
9 CD3E 11.9
bar=donor   line=cohort median 		11.9 12.0 42.8%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 11.1
bar=donor   line=cohort median 		11.0 10.9 72.6%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 11.9
bar=donor   line=cohort median 		11.7 11.7 62.2%
12 GNLY 12.3
bar=donor   line=cohort median 		12.0 12.1 62.5%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.3
bar=donor   line=cohort median 		16.4 16.4 29.2%
17 MT-CO2 15.2
bar=donor   line=cohort median 		15.2 15.3 35.7%
18 MT-ND1 15.1
bar=donor   line=cohort median 		15.0 15.2 31.4%
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