GSM8077473

Dataset: gse255685 • Sample: YZ420 • Status: MDD with drug therapy
◂ Prev All Donors Next ▸

Quality Control Metrics

2 Mean expression score Group median: 2 • 2.0%ile (↓ Low)
22,357 Genes with score > 0 Group median: 22,378 • 23.1%ile (↓ Low)
0 Median expression score Group median: 0 • 27.1%ile (≈ Median)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

43.5Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 2.35
bar=donor   line=cohort median 		2.02 85.1%
FOXO3 Insulin/IGF-1 Signaling 9.43
bar=donor   line=cohort median 		9.99 1.3%
CETP Lipid Metabolism 4.63
bar=donor   line=cohort median 		5.05 7.0%
SIRT6 Sirtuin Family 8.36
bar=donor   line=cohort median 		8.34 58.2%
SIRT1 Sirtuin Family 8.51
bar=donor   line=cohort median 		8.72 21.7%
SIRT3 Sirtuin Family 7.76
bar=donor   line=cohort median 		7.49 92.7%
IGF1R Insulin/IGF-1 Signaling 9.61
bar=donor   line=cohort median 		10.21 7.0%
KLOTHO Anti-aging 2.15
bar=donor   line=cohort median 		2.51 4.8%
APOC3 Lipid Metabolism -1.92
bar=donor   line=cohort median 		-2.11 99.5%
IL6 Inflammation 1.07
bar=donor   line=cohort median 		1.16 26.0%
TERT Telomere Maintenance 1.58
bar=donor   line=cohort median 		1.51 63.6%
IRS2 Insulin/IGF-1 Signaling 9.37
bar=donor   line=cohort median 		9.81 14.5%
TP53 Tumor Suppression 8.85
bar=donor   line=cohort median 		8.92 44.6%
SHC1 Signal Transduction 9.30
bar=donor   line=cohort median 		9.35 32.8%
ACE Signal Transduction 5.17
bar=donor   line=cohort median 		4.64 93.4%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 EEF1A1 17.4 0
2 B2M 16.9 0
3 MT-RNR2 16.9 0
4 MT-CO1 16.8 0
5 ACTB 16.5 0
6 HLA-C 16.2 0
7 HLA-B 16.1 0
8 MT-ND4 15.9 0
9 HLA-E 15.7 0
10 MT-CO3 15.7 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 13.3
bar=donor   line=cohort median 		14.2 14.2 12.0%
2 S100A9 15.0
bar=donor   line=cohort median 		15.4 15.5 15.9%
3 IL1B 9.0
bar=donor   line=cohort median 		9.5 9.3 34.2%
4 CXCL8 11.0
bar=donor   line=cohort median 		10.3 11.4 42.1%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 6.0
bar=donor   line=cohort median 		6.1 6.1 47.8%
6 FCGR3B 13.7
bar=donor   line=cohort median 		14.7 14.7 2.7%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.5
bar=donor   line=cohort median 		14.4 14.3 61.8%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 11.0
bar=donor   line=cohort median 		10.3 10.4 95.2%
9 CD3E 12.6
bar=donor   line=cohort median 		11.9 12.0 97.7%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 10.8
bar=donor   line=cohort median 		10.9 10.9 32.8%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 12.1
bar=donor   line=cohort median 		11.5 11.7 75.4%
12 GNLY 12.1
bar=donor   line=cohort median 		12.0 12.1 49.3%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.8
bar=donor   line=cohort median 		16.4 16.4 95.9%
17 MT-CO2 15.5
bar=donor   line=cohort median 		15.3 15.3 75.4%
18 MT-ND1 15.2
bar=donor   line=cohort median 		15.2 15.2 48.6%
◂ Previous Donor Back to Donor List Next Donor ▸