GSM8077476

Dataset: gse255685 • Sample: YZ431 • Status: MDD with drug therapy
◂ Prev All Donors Next ▸

Quality Control Metrics

2 Mean expression score Group median: 2 • 89.4%ile (↑ High)
22,405 Genes with score > 0 Group median: 22,378 • 78.3%ile (↑ High)
0 Median expression score Group median: 0 • 89.1%ile (↑ High)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

39.8Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 1.92
bar=donor   line=cohort median 		2.02 35.7%
FOXO3 Insulin/IGF-1 Signaling 9.89
bar=donor   line=cohort median 		9.99 35.7%
CETP Lipid Metabolism 5.12
bar=donor   line=cohort median 		5.05 62.5%
SIRT6 Sirtuin Family 8.14
bar=donor   line=cohort median 		8.34 10.2%
SIRT1 Sirtuin Family 8.80
bar=donor   line=cohort median 		8.72 67.2%
SIRT3 Sirtuin Family 7.50
bar=donor   line=cohort median 		7.49 51.4%
IGF1R Insulin/IGF-1 Signaling 10.48
bar=donor   line=cohort median 		10.21 80.5%
KLOTHO Anti-aging 2.87
bar=donor   line=cohort median 		2.51 89.1%
APOC3 Lipid Metabolism -2.12
bar=donor   line=cohort median 		-2.11 3.1%
IL6 Inflammation 0.97
bar=donor   line=cohort median 		1.16 0.5%
TERT Telomere Maintenance 1.39
bar=donor   line=cohort median 		1.51 23.1%
IRS2 Insulin/IGF-1 Signaling 9.43
bar=donor   line=cohort median 		9.81 16.0%
TP53 Tumor Suppression 8.79
bar=donor   line=cohort median 		8.92 37.5%
SHC1 Signal Transduction 9.25
bar=donor   line=cohort median 		9.35 18.1%
ACE Signal Transduction 4.81
bar=donor   line=cohort median 		4.64 66.5%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.3 0
2 B2M 16.8 0
3 EEF1A1 16.5 0
4 ACTB 16.2 0
5 MT-CO1 16.2 0
6 MT-RNR1 15.7 0
7 HLA-B 15.5 0
8 HLA-E 15.5 0
9 HLA-C 15.5 0
10 MT-ND4 15.4 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 14.4
bar=donor   line=cohort median 		14.2 14.2 64.7%
2 S100A9 15.4
bar=donor   line=cohort median 		15.4 15.5 44.3%
3 IL1B 9.8
bar=donor   line=cohort median 		9.5 9.3 79.4%
4 CXCL8 12.4
bar=donor   line=cohort median 		10.3 11.4 83.3%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 6.1
bar=donor   line=cohort median 		6.1 6.1 53.2%
6 FCGR3B 15.0
bar=donor   line=cohort median 		14.7 14.7 75.8%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.4
bar=donor   line=cohort median 		14.4 14.3 51.4%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.2
bar=donor   line=cohort median 		10.3 10.4 30.6%
9 CD3E 11.7
bar=donor   line=cohort median 		11.9 12.0 11.6%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 10.9
bar=donor   line=cohort median 		10.9 10.9 53.6%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 11.4
bar=donor   line=cohort median 		11.5 11.7 28.5%
12 GNLY 12.1
bar=donor   line=cohort median 		12.0 12.1 46.8%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.2
bar=donor   line=cohort median 		16.4 16.4 11.3%
17 MT-CO2 15.0
bar=donor   line=cohort median 		15.3 15.3 11.6%
18 MT-ND1 15.0
bar=donor   line=cohort median 		15.2 15.2 24.2%
◂ Previous Donor Back to Donor List Next Donor ▸