GSM8077477

Dataset: gse255685 • Sample: YZ432 • Status: MDD without drug therapy
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Quality Control Metrics

2 Mean expression score Group median: 2 • 37.8%ile (≈ Median)
22,381 Genes with score > 0 Group median: 22,375 • 55.9%ile (≈ Median)
0 Median expression score Group median: 0 • 56.5%ile (≈ Median)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

57.7Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 2.11
bar=donor   line=cohort median 		2.02 64.3%
FOXO3 Insulin/IGF-1 Signaling 9.99
bar=donor   line=cohort median 		9.99 49.3%
CETP Lipid Metabolism 5.07
bar=donor   line=cohort median 		5.05 53.6%
SIRT6 Sirtuin Family 8.17
bar=donor   line=cohort median 		8.34 15.6%
SIRT1 Sirtuin Family 8.99
bar=donor   line=cohort median 		8.72 93.4%
SIRT3 Sirtuin Family 7.37
bar=donor   line=cohort median 		7.49 29.6%
IGF1R Insulin/IGF-1 Signaling 10.37
bar=donor   line=cohort median 		10.21 69.4%
KLOTHO Anti-aging 2.72
bar=donor   line=cohort median 		2.51 78.3%
APOC3 Lipid Metabolism -2.08
bar=donor   line=cohort median 		-2.11 94.4%
IL6 Inflammation 0.97
bar=donor   line=cohort median 		1.16 0.9%
TERT Telomere Maintenance 1.73
bar=donor   line=cohort median 		1.51 86.2%
IRS2 Insulin/IGF-1 Signaling 9.47
bar=donor   line=cohort median 		9.81 20.3%
TP53 Tumor Suppression 9.00
bar=donor   line=cohort median 		8.92 62.9%
SHC1 Signal Transduction 9.34
bar=donor   line=cohort median 		9.35 48.2%
ACE Signal Transduction 5.68
bar=donor   line=cohort median 		4.64 99.8%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.4 0
2 B2M 16.8 0
3 EEF1A1 16.7 0
4 MT-CO1 16.6 0
5 ACTB 16.6 0
6 HLA-C 16.1 0
7 MT-RNR1 16.0 0
8 HLA-B 15.8 0
9 HLA-E 15.6 0
10 MT-ND4 15.5 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 13.9
bar=donor   line=cohort median 		13.8 14.2 31.0%
2 S100A9 15.3
bar=donor   line=cohort median 		15.3 15.5 32.4%
3 IL1B 9.3
bar=donor   line=cohort median 		9.5 9.3 52.2%
4 CXCL8 11.1
bar=donor   line=cohort median 		10.6 11.4 45.0%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 7.4
bar=donor   line=cohort median 		6.0 6.1 93.0%
6 FCGR3B 14.7
bar=donor   line=cohort median 		14.6 14.7 53.2%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.6
bar=donor   line=cohort median 		14.3 14.3 74.7%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.2
bar=donor   line=cohort median 		10.2 10.4 31.4%
9 CD3E 11.8
bar=donor   line=cohort median 		11.9 12.0 21.7%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 11.2
bar=donor   line=cohort median 		11.0 10.9 83.3%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 11.4
bar=donor   line=cohort median 		11.7 11.7 23.8%
12 GNLY 11.6
bar=donor   line=cohort median 		12.0 12.1 14.5%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.6
bar=donor   line=cohort median 		16.4 16.4 78.7%
17 MT-CO2 15.2
bar=donor   line=cohort median 		15.2 15.3 36.7%
18 MT-ND1 15.1
bar=donor   line=cohort median 		15.0 15.2 26.7%
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