GSM8077479

Dataset: gse255685 • Sample: YZ449 • Status: MDD without drug therapy
◂ Prev All Donors Next ▸

Quality Control Metrics

2 Mean expression score Group median: 2 • 86.9%ile (↑ High)
22,438 Genes with score > 0 Group median: 22,375 • 95.0%ile (↑ High)
0 Median expression score Group median: 0 • 79.7%ile (↑ High)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

44.8Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 2.16
bar=donor   line=cohort median 		2.02 72.2%
FOXO3 Insulin/IGF-1 Signaling 9.98
bar=donor   line=cohort median 		9.99 48.2%
CETP Lipid Metabolism 4.95
bar=donor   line=cohort median 		5.05 39.3%
SIRT6 Sirtuin Family 8.27
bar=donor   line=cohort median 		8.34 32.8%
SIRT1 Sirtuin Family 8.51
bar=donor   line=cohort median 		8.72 21.3%
SIRT3 Sirtuin Family 7.76
bar=donor   line=cohort median 		7.49 92.3%
IGF1R Insulin/IGF-1 Signaling 10.24
bar=donor   line=cohort median 		10.21 53.6%
KLOTHO Anti-aging 2.73
bar=donor   line=cohort median 		2.51 80.1%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 42.5%
IL6 Inflammation 1.08
bar=donor   line=cohort median 		1.16 29.6%
TERT Telomere Maintenance 1.37
bar=donor   line=cohort median 		1.51 17.7%
IRS2 Insulin/IGF-1 Signaling 9.61
bar=donor   line=cohort median 		9.81 29.9%
TP53 Tumor Suppression 8.75
bar=donor   line=cohort median 		8.92 32.1%
SHC1 Signal Transduction 9.41
bar=donor   line=cohort median 		9.35 69.7%
ACE Signal Transduction 4.24
bar=donor   line=cohort median 		4.64 10.6%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.1 0
2 B2M 16.9 0
3 EEF1A1 16.8 0
4 MT-CO1 16.6 0
5 ACTB 16.5 0
6 HLA-C 16.1 0
7 MT-ND4 15.8 0
8 S100A9 15.7 0
9 HLA-B 15.7 0
10 TMSB4X 15.6 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 14.8
bar=donor   line=cohort median 		13.8 14.2 85.8%
2 S100A9 15.7
bar=donor   line=cohort median 		15.3 15.5 67.2%
3 IL1B 8.7
bar=donor   line=cohort median 		9.5 9.3 22.4%
4 CXCL8 11.6
bar=donor   line=cohort median 		10.6 11.4 55.7%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 9.2
bar=donor   line=cohort median 		6.0 6.1 99.8%
6 FCGR3B 14.3
bar=donor   line=cohort median 		14.6 14.7 18.5%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 15.0
bar=donor   line=cohort median 		14.3 14.3 95.5%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.2
bar=donor   line=cohort median 		10.2 10.4 28.5%
9 CD3E 11.6
bar=donor   line=cohort median 		11.9 12.0 3.4%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 10.6
bar=donor   line=cohort median 		11.0 10.9 18.8%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 11.4
bar=donor   line=cohort median 		11.7 11.7 21.7%
12 GNLY 11.8
bar=donor   line=cohort median 		12.0 12.1 21.3%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.6
bar=donor   line=cohort median 		16.4 16.4 85.5%
17 MT-CO2 15.5
bar=donor   line=cohort median 		15.2 15.3 70.4%
18 MT-ND1 15.2
bar=donor   line=cohort median 		15.0 15.2 53.9%
◂ Previous Donor Back to Donor List Next Donor ▸