GSM8077483

Dataset: gse255685 • Sample: YZ456 • Status: MDD with drug therapy
◂ Prev All Donors Next ▸

Quality Control Metrics

2 Mean expression score Group median: 2 • 24.2%ile (↓ Low)
22,349 Genes with score > 0 Group median: 22,378 • 13.6%ile (↓ Low)
0 Median expression score Group median: 0 • 35.3%ile (≈ Median)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

55.5Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 2.09
bar=donor   line=cohort median 		2.02 62.9%
FOXO3 Insulin/IGF-1 Signaling 10.05
bar=donor   line=cohort median 		9.99 57.9%
CETP Lipid Metabolism 5.24
bar=donor   line=cohort median 		5.05 76.2%
SIRT6 Sirtuin Family 8.45
bar=donor   line=cohort median 		8.34 69.7%
SIRT1 Sirtuin Family 8.69
bar=donor   line=cohort median 		8.72 46.1%
SIRT3 Sirtuin Family 7.60
bar=donor   line=cohort median 		7.49 69.7%
IGF1R Insulin/IGF-1 Signaling 10.35
bar=donor   line=cohort median 		10.21 67.6%
KLOTHO Anti-aging 2.53
bar=donor   line=cohort median 		2.51 54.3%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 71.9%
IL6 Inflammation 1.11
bar=donor   line=cohort median 		1.16 36.7%
TERT Telomere Maintenance 1.58
bar=donor   line=cohort median 		1.51 64.3%
IRS2 Insulin/IGF-1 Signaling 9.66
bar=donor   line=cohort median 		9.81 34.6%
TP53 Tumor Suppression 8.97
bar=donor   line=cohort median 		8.92 59.3%
SHC1 Signal Transduction 9.31
bar=donor   line=cohort median 		9.35 38.2%
ACE Signal Transduction 4.37
bar=donor   line=cohort median 		4.64 23.1%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.5 0
2 B2M 17.1 0
3 ACTB 16.8 0
4 EEF1A1 16.7 0
5 S100A9 16.4 0
6 MT-CO1 16.3 0
7 HLA-B 16.2 0
8 HLA-C 16.2 0
9 MT-RNR1 16.0 0
10 HLA-E 15.9 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 15.4
bar=donor   line=cohort median 		14.2 14.2 97.7%
2 S100A9 16.4
bar=donor   line=cohort median 		15.4 15.5 93.7%
3 IL1B 9.8
bar=donor   line=cohort median 		9.5 9.3 78.0%
4 CXCL8 9.1
bar=donor   line=cohort median 		10.3 11.4 13.1%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 7.6
bar=donor   line=cohort median 		6.1 6.1 93.7%
6 FCGR3B 15.4
bar=donor   line=cohort median 		14.7 14.7 93.0%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 15.1
bar=donor   line=cohort median 		14.4 14.3 98.7%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.2
bar=donor   line=cohort median 		10.3 10.4 26.0%
9 CD3E 11.8
bar=donor   line=cohort median 		11.9 12.0 20.3%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 10.7
bar=donor   line=cohort median 		10.9 10.9 28.9%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 11.6
bar=donor   line=cohort median 		11.5 11.7 42.1%
12 GNLY 11.9
bar=donor   line=cohort median 		12.0 12.1 37.8%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.3
bar=donor   line=cohort median 		16.4 16.4 18.8%
17 MT-CO2 15.2
bar=donor   line=cohort median 		15.3 15.3 29.2%
18 MT-ND1 15.0
bar=donor   line=cohort median 		15.2 15.2 21.7%
◂ Previous Donor Back to Donor List Next Donor ▸