GSM8077484

Dataset: gse255685 • Sample: YZ461 • Status: MDD without drug therapy
◂ Prev All Donors Next ▸

Quality Control Metrics

2 Mean expression score Group median: 2 • 32.1%ile (≈ Median)
22,380 Genes with score > 0 Group median: 22,375 • 53.8%ile (≈ Median)
0 Median expression score Group median: 0 • 40.3%ile (≈ Median)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

52.0Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 2.15
bar=donor   line=cohort median 		2.02 70.1%
FOXO3 Insulin/IGF-1 Signaling 10.05
bar=donor   line=cohort median 		9.99 58.2%
CETP Lipid Metabolism 5.05
bar=donor   line=cohort median 		5.05 51.1%
SIRT6 Sirtuin Family 8.36
bar=donor   line=cohort median 		8.34 56.5%
SIRT1 Sirtuin Family 8.88
bar=donor   line=cohort median 		8.72 80.1%
SIRT3 Sirtuin Family 7.30
bar=donor   line=cohort median 		7.49 16.7%
IGF1R Insulin/IGF-1 Signaling 10.63
bar=donor   line=cohort median 		10.21 90.5%
KLOTHO Anti-aging 2.82
bar=donor   line=cohort median 		2.51 87.3%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 38.5%
IL6 Inflammation 1.08
bar=donor   line=cohort median 		1.16 28.9%
TERT Telomere Maintenance 1.52
bar=donor   line=cohort median 		1.51 52.5%
IRS2 Insulin/IGF-1 Signaling 9.72
bar=donor   line=cohort median 		9.81 40.7%
TP53 Tumor Suppression 8.94
bar=donor   line=cohort median 		8.92 54.3%
SHC1 Signal Transduction 9.26
bar=donor   line=cohort median 		9.35 20.6%
ACE Signal Transduction 4.47
bar=donor   line=cohort median 		4.64 33.5%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.3 0
2 B2M 16.9 0
3 EEF1A1 16.7 0
4 ACTB 16.4 0
5 MT-CO1 16.4 0
6 HLA-C 16.1 0
7 FCGR3B 15.7 0
8 MT-RNR1 15.7 0
9 HLA-E 15.7 0
10 FTL 15.6 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 14.1
bar=donor   line=cohort median 		13.8 14.2 43.5%
2 S100A9 15.4
bar=donor   line=cohort median 		15.3 15.5 43.2%
3 IL1B 10.2
bar=donor   line=cohort median 		9.5 9.3 93.7%
4 CXCL8 11.3
bar=donor   line=cohort median 		10.6 11.4 47.8%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 6.5
bar=donor   line=cohort median 		6.0 6.1 71.5%
6 FCGR3B 15.7
bar=donor   line=cohort median 		14.6 14.7 98.7%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.3
bar=donor   line=cohort median 		14.3 14.3 48.9%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.3
bar=donor   line=cohort median 		10.2 10.4 45.7%
9 CD3E 12.0
bar=donor   line=cohort median 		11.9 12.0 47.8%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 10.8
bar=donor   line=cohort median 		11.0 10.9 35.3%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 11.4
bar=donor   line=cohort median 		11.7 11.7 30.3%
12 GNLY 12.3
bar=donor   line=cohort median 		12.0 12.1 67.2%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.4
bar=donor   line=cohort median 		16.4 16.4 46.1%
17 MT-CO2 15.1
bar=donor   line=cohort median 		15.2 15.3 21.7%
18 MT-ND1 15.1
bar=donor   line=cohort median 		15.0 15.2 27.4%
◂ Previous Donor Back to Donor List Next Donor ▸