GSM8077490

Dataset: gse255685 • Sample: YZ482 • Status: MDD with drug therapy
◂ Prev All Donors Next ▸

Quality Control Metrics

2 Mean expression score Group median: 2 • 71.9%ile (≈ Median)
22,429 Genes with score > 0 Group median: 22,378 • 93.4%ile (↑ High)
0 Median expression score Group median: 0 • 95.2%ile (↑ High)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

41.4Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 1.81
bar=donor   line=cohort median 		2.02 16.0%
FOXO3 Insulin/IGF-1 Signaling 10.25
bar=donor   line=cohort median 		9.99 86.9%
CETP Lipid Metabolism 4.64
bar=donor   line=cohort median 		5.05 7.4%
SIRT6 Sirtuin Family 8.30
bar=donor   line=cohort median 		8.34 40.0%
SIRT1 Sirtuin Family 8.62
bar=donor   line=cohort median 		8.72 38.2%
SIRT3 Sirtuin Family 7.51
bar=donor   line=cohort median 		7.49 55.4%
IGF1R Insulin/IGF-1 Signaling 10.25
bar=donor   line=cohort median 		10.21 54.3%
KLOTHO Anti-aging 2.34
bar=donor   line=cohort median 		2.51 24.9%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 54.7%
IL6 Inflammation 1.71
bar=donor   line=cohort median 		1.16 97.7%
TERT Telomere Maintenance 1.29
bar=donor   line=cohort median 		1.51 3.8%
IRS2 Insulin/IGF-1 Signaling 10.13
bar=donor   line=cohort median 		9.81 70.1%
TP53 Tumor Suppression 8.42
bar=donor   line=cohort median 		8.92 3.4%
SHC1 Signal Transduction 9.26
bar=donor   line=cohort median 		9.35 19.5%
ACE Signal Transduction 4.62
bar=donor   line=cohort median 		4.64 48.9%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.7 0
2 B2M 17.1 0
3 EEF1A1 16.9 0
4 MT-CO1 16.6 0
5 ACTB 16.4 0
6 MT-RNR1 16.1 0
7 HLA-B 16.1 0
8 MT-ND4 15.9 0
9 S100A9 15.8 0
10 HLA-E 15.8 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 14.6
bar=donor   line=cohort median 		14.2 14.2 79.4%
2 S100A9 15.8
bar=donor   line=cohort median 		15.4 15.5 73.3%
3 IL1B 9.1
bar=donor   line=cohort median 		9.5 9.3 38.9%
4 CXCL8 12.2
bar=donor   line=cohort median 		10.3 11.4 75.4%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 5.7
bar=donor   line=cohort median 		6.1 6.1 20.6%
6 FCGR3B 14.7
bar=donor   line=cohort median 		14.7 14.7 50.4%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.6
bar=donor   line=cohort median 		14.4 14.3 75.4%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.3
bar=donor   line=cohort median 		10.3 10.4 43.5%
9 CD3E 11.8
bar=donor   line=cohort median 		11.9 12.0 25.3%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 11.2
bar=donor   line=cohort median 		10.9 10.9 81.2%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 10.9
bar=donor   line=cohort median 		11.5 11.7 2.0%
12 GNLY 11.9
bar=donor   line=cohort median 		12.0 12.1 33.9%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.6
bar=donor   line=cohort median 		16.4 16.4 77.6%
17 MT-CO2 15.6
bar=donor   line=cohort median 		15.3 15.3 84.8%
18 MT-ND1 15.5
bar=donor   line=cohort median 		15.2 15.2 84.1%
◂ Previous Donor Back to Donor List Next Donor ▸