GSM8077491

Dataset: gse255685 • Sample: YZ484 • Status: MDD with drug therapy
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Quality Control Metrics

2 Mean expression score Group median: 2 • 42.5%ile (≈ Median)
22,374 Genes with score > 0 Group median: 22,378 • 43.9%ile (≈ Median)
0 Median expression score Group median: 0 • 44.3%ile (≈ Median)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

56.8Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 1.86
bar=donor   line=cohort median 		2.02 24.2%
FOXO3 Insulin/IGF-1 Signaling 10.26
bar=donor   line=cohort median 		9.99 87.3%
CETP Lipid Metabolism 4.96
bar=donor   line=cohort median 		5.05 40.0%
SIRT6 Sirtuin Family 8.54
bar=donor   line=cohort median 		8.34 82.3%
SIRT1 Sirtuin Family 8.54
bar=donor   line=cohort median 		8.72 25.3%
SIRT3 Sirtuin Family 7.60
bar=donor   line=cohort median 		7.49 69.0%
IGF1R Insulin/IGF-1 Signaling 10.40
bar=donor   line=cohort median 		10.21 71.5%
KLOTHO Anti-aging 2.51
bar=donor   line=cohort median 		2.51 50.4%
APOC3 Lipid Metabolism -2.10
bar=donor   line=cohort median 		-2.11 85.5%
IL6 Inflammation 1.14
bar=donor   line=cohort median 		1.16 42.5%
TERT Telomere Maintenance 1.62
bar=donor   line=cohort median 		1.51 74.0%
IRS2 Insulin/IGF-1 Signaling 10.41
bar=donor   line=cohort median 		9.81 81.2%
TP53 Tumor Suppression 8.50
bar=donor   line=cohort median 		8.92 8.8%
SHC1 Signal Transduction 9.27
bar=donor   line=cohort median 		9.35 23.1%
ACE Signal Transduction 5.06
bar=donor   line=cohort median 		4.64 87.3%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.5 0
2 B2M 17.3 0
3 EEF1A1 16.9 0
4 ACTB 16.6 0
5 HLA-C 16.4 0
6 MT-CO1 16.4 0
7 FTL 16.1 0
8 HLA-B 16.1 0
9 UBA52 16.0 0
10 S100A9 15.9 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 14.9
bar=donor   line=cohort median 		14.2 14.2 90.1%
2 S100A9 15.9
bar=donor   line=cohort median 		15.4 15.5 77.2%
3 IL1B 9.0
bar=donor   line=cohort median 		9.5 9.3 37.8%
4 CXCL8 12.2
bar=donor   line=cohort median 		10.3 11.4 74.4%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 6.4
bar=donor   line=cohort median 		6.1 6.1 70.4%
6 FCGR3B 15.2
bar=donor   line=cohort median 		14.7 14.7 83.7%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 15.0
bar=donor   line=cohort median 		14.4 14.3 94.8%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.4
bar=donor   line=cohort median 		10.3 10.4 50.4%
9 CD3E 11.9
bar=donor   line=cohort median 		11.9 12.0 35.7%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 10.1
bar=donor   line=cohort median 		10.9 10.9 1.6%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 11.3
bar=donor   line=cohort median 		11.5 11.7 15.6%
12 GNLY 11.6
bar=donor   line=cohort median 		12.0 12.1 15.9%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.4
bar=donor   line=cohort median 		16.4 16.4 36.4%
17 MT-CO2 15.4
bar=donor   line=cohort median 		15.3 15.3 63.3%
18 MT-ND1 15.4
bar=donor   line=cohort median 		15.2 15.2 74.7%
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