GSM8077500

Dataset: gse255685 • Sample: YZ505 • Status: MDD with drug therapy
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Quality Control Metrics

2 Mean expression score Group median: 2 • 52.2%ile (≈ Median)
22,361 Genes with score > 0 Group median: 22,378 • 27.4%ile (≈ Median)
0 Median expression score Group median: 0 • 41.0%ile (≈ Median)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

48.6Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 1.75
bar=donor   line=cohort median 		2.02 7.4%
FOXO3 Insulin/IGF-1 Signaling 9.99
bar=donor   line=cohort median 		9.99 50.0%
CETP Lipid Metabolism 5.24
bar=donor   line=cohort median 		5.05 75.8%
SIRT6 Sirtuin Family 8.24
bar=donor   line=cohort median 		8.34 27.8%
SIRT1 Sirtuin Family 8.73
bar=donor   line=cohort median 		8.72 52.9%
SIRT3 Sirtuin Family 7.29
bar=donor   line=cohort median 		7.49 14.9%
IGF1R Insulin/IGF-1 Signaling 10.40
bar=donor   line=cohort median 		10.21 71.9%
KLOTHO Anti-aging 2.33
bar=donor   line=cohort median 		2.51 23.8%
APOC3 Lipid Metabolism -2.10
bar=donor   line=cohort median 		-2.11 83.3%
IL6 Inflammation 1.24
bar=donor   line=cohort median 		1.16 64.3%
TERT Telomere Maintenance 1.61
bar=donor   line=cohort median 		1.51 72.9%
IRS2 Insulin/IGF-1 Signaling 9.37
bar=donor   line=cohort median 		9.81 14.2%
TP53 Tumor Suppression 9.08
bar=donor   line=cohort median 		8.92 75.1%
SHC1 Signal Transduction 9.17
bar=donor   line=cohort median 		9.35 6.6%
ACE Signal Transduction 5.07
bar=donor   line=cohort median 		4.64 88.0%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.6 0
2 B2M 16.8 0
3 EEF1A1 16.6 0
4 MT-CO1 16.5 0
5 ACTB 16.3 0
6 HLA-C 15.9 0
7 FKBP8 15.9 0
8 FTL 15.8 0
9 MT-RNR1 15.8 0
10 MT-ND4 15.8 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 14.5
bar=donor   line=cohort median 		14.2 14.2 71.1%
2 S100A9 15.6
bar=donor   line=cohort median 		15.4 15.5 52.2%
3 IL1B 9.2
bar=donor   line=cohort median 		9.5 9.3 42.1%
4 CXCL8 9.0
bar=donor   line=cohort median 		10.3 11.4 10.9%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 6.5
bar=donor   line=cohort median 		6.1 6.1 73.7%
6 FCGR3B 14.5
bar=donor   line=cohort median 		14.7 14.7 33.2%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 13.9
bar=donor   line=cohort median 		14.4 14.3 15.9%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.4
bar=donor   line=cohort median 		10.3 10.4 57.2%
9 CD3E 11.9
bar=donor   line=cohort median 		11.9 12.0 45.0%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 10.9
bar=donor   line=cohort median 		10.9 10.9 49.6%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 11.6
bar=donor   line=cohort median 		11.5 11.7 41.8%
12 GNLY 12.6
bar=donor   line=cohort median 		12.0 12.1 80.8%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.5
bar=donor   line=cohort median 		16.4 16.4 66.5%
17 MT-CO2 15.4
bar=donor   line=cohort median 		15.3 15.3 57.2%
18 MT-ND1 15.2
bar=donor   line=cohort median 		15.2 15.2 57.2%
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