GSM8077501

Dataset: gse255685 • Sample: YZ507 • Status: MDD with drug therapy
◂ Prev All Donors Next ▸

Quality Control Metrics

2 Mean expression score Group median: 2 • 90.1%ile (↑ High)
22,405 Genes with score > 0 Group median: 22,378 • 78.3%ile (↑ High)
0 Median expression score Group median: 0 • 90.1%ile (↑ High)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

51.2Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 2.10
bar=donor   line=cohort median 		2.02 63.6%
FOXO3 Insulin/IGF-1 Signaling 10.47
bar=donor   line=cohort median 		9.99 95.5%
CETP Lipid Metabolism 5.41
bar=donor   line=cohort median 		5.05 87.3%
SIRT6 Sirtuin Family 8.28
bar=donor   line=cohort median 		8.34 35.3%
SIRT1 Sirtuin Family 8.49
bar=donor   line=cohort median 		8.72 19.5%
SIRT3 Sirtuin Family 7.60
bar=donor   line=cohort median 		7.49 67.9%
IGF1R Insulin/IGF-1 Signaling 10.11
bar=donor   line=cohort median 		10.21 40.0%
KLOTHO Anti-aging 2.33
bar=donor   line=cohort median 		2.51 22.0%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 47.1%
IL6 Inflammation 1.09
bar=donor   line=cohort median 		1.16 31.0%
TERT Telomere Maintenance 1.53
bar=donor   line=cohort median 		1.51 54.3%
IRS2 Insulin/IGF-1 Signaling 10.73
bar=donor   line=cohort median 		9.81 90.9%
TP53 Tumor Suppression 8.21
bar=donor   line=cohort median 		8.92 0.2%
SHC1 Signal Transduction 9.38
bar=donor   line=cohort median 		9.35 61.1%
ACE Signal Transduction 4.68
bar=donor   line=cohort median 		4.64 52.9%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.5 0
2 B2M 17.3 0
3 EEF1A1 16.7 0
4 ACTB 16.4 0
5 HLA-C 16.3 0
6 MT-CO1 16.2 0
7 HLA-B 16.0 0
8 HLA-E 16.0 0
9 S100A9 15.9 0
10 MT-RNR1 15.8 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 14.7
bar=donor   line=cohort median 		14.2 14.2 82.3%
2 S100A9 15.9
bar=donor   line=cohort median 		15.4 15.5 74.0%
3 IL1B 9.4
bar=donor   line=cohort median 		9.5 9.3 55.4%
4 CXCL8 11.0
bar=donor   line=cohort median 		10.3 11.4 42.8%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 6.1
bar=donor   line=cohort median 		6.1 6.1 49.6%
6 FCGR3B 15.4
bar=donor   line=cohort median 		14.7 14.7 95.5%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 15.1
bar=donor   line=cohort median 		14.4 14.3 97.0%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.2
bar=donor   line=cohort median 		10.3 10.4 24.9%
9 CD3E 11.7
bar=donor   line=cohort median 		11.9 12.0 6.6%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 10.8
bar=donor   line=cohort median 		10.9 10.9 30.3%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 11.2
bar=donor   line=cohort median 		11.5 11.7 9.9%
12 GNLY 11.8
bar=donor   line=cohort median 		12.0 12.1 25.6%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.2
bar=donor   line=cohort median 		16.4 16.4 9.1%
17 MT-CO2 15.2
bar=donor   line=cohort median 		15.3 15.3 30.6%
18 MT-ND1 15.3
bar=donor   line=cohort median 		15.2 15.2 67.2%
◂ Previous Donor Back to Donor List Next Donor ▸