GSM8077502

Dataset: gse255685 • Sample: YZ508 • Status: MDD without drug therapy
◂ Prev All Donors Next ▸

Quality Control Metrics

2 Mean expression score Group median: 2 • 67.2%ile (≈ Median)
22,384 Genes with score > 0 Group median: 22,375 • 59.9%ile (≈ Median)
0 Median expression score Group median: 0 • 59.0%ile (≈ Median)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

46.5Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 1.87
bar=donor   line=cohort median 		2.02 24.6%
FOXO3 Insulin/IGF-1 Signaling 10.13
bar=donor   line=cohort median 		9.99 73.7%
CETP Lipid Metabolism 5.28
bar=donor   line=cohort median 		5.05 78.3%
SIRT6 Sirtuin Family 8.49
bar=donor   line=cohort median 		8.34 76.5%
SIRT1 Sirtuin Family 8.78
bar=donor   line=cohort median 		8.72 62.2%
SIRT3 Sirtuin Family 7.14
bar=donor   line=cohort median 		7.49 4.5%
IGF1R Insulin/IGF-1 Signaling 10.13
bar=donor   line=cohort median 		10.21 42.8%
KLOTHO Anti-aging 2.44
bar=donor   line=cohort median 		2.51 40.7%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 33.2%
IL6 Inflammation 0.99
bar=donor   line=cohort median 		1.16 4.8%
TERT Telomere Maintenance 1.36
bar=donor   line=cohort median 		1.51 16.3%
IRS2 Insulin/IGF-1 Signaling 10.08
bar=donor   line=cohort median 		9.81 67.9%
TP53 Tumor Suppression 8.85
bar=donor   line=cohort median 		8.92 44.3%
SHC1 Signal Transduction 9.52
bar=donor   line=cohort median 		9.35 88.7%
ACE Signal Transduction 4.54
bar=donor   line=cohort median 		4.64 39.6%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.4 0
2 B2M 17.3 0
3 ACTB 16.8 0
4 EEF1A1 16.6 0
5 MT-CO1 16.5 0
6 HLA-B 16.3 0
7 HLA-C 16.2 0
8 MT-RNR1 16.0 0
9 HLA-E 16.0 0
10 S100A9 15.8 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 14.3
bar=donor   line=cohort median 		13.8 14.2 57.9%
2 S100A9 15.8
bar=donor   line=cohort median 		15.3 15.5 73.7%
3 IL1B 9.5
bar=donor   line=cohort median 		9.5 9.3 60.4%
4 CXCL8 12.0
bar=donor   line=cohort median 		10.6 11.4 70.4%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 6.6
bar=donor   line=cohort median 		6.0 6.1 75.8%
6 FCGR3B 15.1
bar=donor   line=cohort median 		14.6 14.7 79.4%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 15.2
bar=donor   line=cohort median 		14.3 14.3 99.5%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.1
bar=donor   line=cohort median 		10.2 10.4 17.7%
9 CD3E 11.5
bar=donor   line=cohort median 		11.9 12.0 1.6%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 10.5
bar=donor   line=cohort median 		11.0 10.9 11.3%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 11.8
bar=donor   line=cohort median 		11.7 11.7 56.8%
12 GNLY 12.0
bar=donor   line=cohort median 		12.0 12.1 43.9%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.5
bar=donor   line=cohort median 		16.4 16.4 60.4%
17 MT-CO2 15.2
bar=donor   line=cohort median 		15.2 15.3 37.1%
18 MT-ND1 15.2
bar=donor   line=cohort median 		15.0 15.2 55.4%
◂ Previous Donor Back to Donor List Next Donor ▸