GSM8077518

Dataset: gse255685 • Sample: YZ552 • Status: MDD with drug therapy
◂ Prev All Donors Next ▸

Quality Control Metrics

2 Mean expression score Group median: 2 • 55.7%ile (≈ Median)
22,366 Genes with score > 0 Group median: 22,378 • 33.9%ile (≈ Median)
0 Median expression score Group median: 0 • 47.8%ile (≈ Median)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

53.9Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 2.01
bar=donor   line=cohort median 		2.02 48.6%
FOXO3 Insulin/IGF-1 Signaling 10.12
bar=donor   line=cohort median 		9.99 70.8%
CETP Lipid Metabolism 5.19
bar=donor   line=cohort median 		5.05 69.7%
SIRT6 Sirtuin Family 8.20
bar=donor   line=cohort median 		8.34 17.7%
SIRT1 Sirtuin Family 8.89
bar=donor   line=cohort median 		8.72 82.3%
SIRT3 Sirtuin Family 7.50
bar=donor   line=cohort median 		7.49 52.5%
IGF1R Insulin/IGF-1 Signaling 10.16
bar=donor   line=cohort median 		10.21 44.3%
KLOTHO Anti-aging 2.83
bar=donor   line=cohort median 		2.51 88.0%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 71.2%
IL6 Inflammation 1.21
bar=donor   line=cohort median 		1.16 60.4%
TERT Telomere Maintenance 1.40
bar=donor   line=cohort median 		1.51 24.6%
IRS2 Insulin/IGF-1 Signaling 9.77
bar=donor   line=cohort median 		9.81 45.0%
TP53 Tumor Suppression 8.92
bar=donor   line=cohort median 		8.92 49.6%
SHC1 Signal Transduction 9.24
bar=donor   line=cohort median 		9.35 14.2%
ACE Signal Transduction 4.84
bar=donor   line=cohort median 		4.64 69.7%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 18.0 0
2 B2M 17.0 0
3 EEF1A1 16.6 0
4 ACTB 16.5 0
5 MT-RNR1 16.4 0
6 MT-CO1 16.4 0
7 HLA-C 16.1 0
8 FTL 15.8 0
9 MT-ND4 15.8 0
10 HLA-B 15.8 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 14.6
bar=donor   line=cohort median 		14.2 14.2 75.4%
2 S100A9 15.7
bar=donor   line=cohort median 		15.4 15.5 62.9%
3 IL1B 9.9
bar=donor   line=cohort median 		9.5 9.3 80.1%
4 CXCL8 11.2
bar=donor   line=cohort median 		10.3 11.4 46.8%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 5.8
bar=donor   line=cohort median 		6.1 6.1 25.3%
6 FCGR3B 14.8
bar=donor   line=cohort median 		14.7 14.7 61.8%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.9
bar=donor   line=cohort median 		14.4 14.3 90.1%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.2
bar=donor   line=cohort median 		10.3 10.4 26.3%
9 CD3E 11.7
bar=donor   line=cohort median 		11.9 12.0 12.4%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 10.9
bar=donor   line=cohort median 		10.9 10.9 47.8%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 11.3
bar=donor   line=cohort median 		11.5 11.7 20.3%
12 GNLY 12.4
bar=donor   line=cohort median 		12.0 12.1 71.1%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.4
bar=donor   line=cohort median 		16.4 16.4 39.6%
17 MT-CO2 15.4
bar=donor   line=cohort median 		15.3 15.3 59.3%
18 MT-ND1 15.4
bar=donor   line=cohort median 		15.2 15.2 72.9%
◂ Previous Donor Back to Donor List Next Donor ▸