GSM8077519

Dataset: gse255685 • Sample: YZ558 • Status: MDD with drug therapy
◂ Prev All Donors Next ▸

Quality Control Metrics

2 Mean expression score Group median: 2 • 86.2%ile (↑ High)
22,415 Genes with score > 0 Group median: 22,378 • 87.1%ile (↑ High)
0 Median expression score Group median: 0 • 86.6%ile (↑ High)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

52.1Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 1.90
bar=donor   line=cohort median 		2.02 32.4%
FOXO3 Insulin/IGF-1 Signaling 10.43
bar=donor   line=cohort median 		9.99 94.4%
CETP Lipid Metabolism 5.30
bar=donor   line=cohort median 		5.05 79.8%
SIRT6 Sirtuin Family 8.17
bar=donor   line=cohort median 		8.34 16.3%
SIRT1 Sirtuin Family 8.98
bar=donor   line=cohort median 		8.72 92.3%
SIRT3 Sirtuin Family 7.31
bar=donor   line=cohort median 		7.49 17.4%
IGF1R Insulin/IGF-1 Signaling 10.63
bar=donor   line=cohort median 		10.21 90.9%
KLOTHO Anti-aging 2.97
bar=donor   line=cohort median 		2.51 94.8%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 59.7%
IL6 Inflammation 1.00
bar=donor   line=cohort median 		1.16 11.7%
TERT Telomere Maintenance 1.55
bar=donor   line=cohort median 		1.51 58.6%
IRS2 Insulin/IGF-1 Signaling 9.73
bar=donor   line=cohort median 		9.81 42.1%
TP53 Tumor Suppression 8.85
bar=donor   line=cohort median 		8.92 43.9%
SHC1 Signal Transduction 9.27
bar=donor   line=cohort median 		9.35 22.8%
ACE Signal Transduction 4.38
bar=donor   line=cohort median 		4.64 23.8%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.5 0
2 B2M 17.0 0
3 ACTB 16.4 0
4 EEF1A1 16.3 0
5 HLA-C 16.1 0
6 MT-CO1 16.0 0
7 MT-RNR1 15.9 0
8 CSF3R 15.8 0
9 HLA-E 15.8 0
10 S100A9 15.7 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 14.7
bar=donor   line=cohort median 		14.2 14.2 81.9%
2 S100A9 15.7
bar=donor   line=cohort median 		15.4 15.5 63.3%
3 IL1B 10.0
bar=donor   line=cohort median 		9.5 9.3 86.9%
4 CXCL8 11.1
bar=donor   line=cohort median 		10.3 11.4 43.9%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 5.9
bar=donor   line=cohort median 		6.1 6.1 38.9%
6 FCGR3B 15.3
bar=donor   line=cohort median 		14.7 14.7 89.1%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 13.7
bar=donor   line=cohort median 		14.4 14.3 6.6%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.1
bar=donor   line=cohort median 		10.3 10.4 19.9%
9 CD3E 11.6
bar=donor   line=cohort median 		11.9 12.0 5.9%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 11.0
bar=donor   line=cohort median 		10.9 10.9 67.2%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 11.5
bar=donor   line=cohort median 		11.5 11.7 37.1%
12 GNLY 12.1
bar=donor   line=cohort median 		12.0 12.1 50.4%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.0
bar=donor   line=cohort median 		16.4 16.4 0.5%
17 MT-CO2 15.0
bar=donor   line=cohort median 		15.3 15.3 13.8%
18 MT-ND1 15.1
bar=donor   line=cohort median 		15.2 15.2 29.2%
◂ Previous Donor Back to Donor List Next Donor ▸