GSM8077522

Dataset: gse255685 • Sample: YZ564 • Status: MDD without drug therapy
◂ Prev All Donors Next ▸

Quality Control Metrics

2 Mean expression score Group median: 2 • 67.9%ile (≈ Median)
22,432 Genes with score > 0 Group median: 22,375 • 93.7%ile (↑ High)
0 Median expression score Group median: 0 • 85.5%ile (↑ High)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

45.7Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 2.16
bar=donor   line=cohort median 		2.02 71.5%
FOXO3 Insulin/IGF-1 Signaling 10.08
bar=donor   line=cohort median 		9.99 62.9%
CETP Lipid Metabolism 4.76
bar=donor   line=cohort median 		5.05 17.0%
SIRT6 Sirtuin Family 8.31
bar=donor   line=cohort median 		8.34 40.3%
SIRT1 Sirtuin Family 8.40
bar=donor   line=cohort median 		8.72 10.9%
SIRT3 Sirtuin Family 7.67
bar=donor   line=cohort median 		7.49 81.2%
IGF1R Insulin/IGF-1 Signaling 9.74
bar=donor   line=cohort median 		10.21 12.7%
KLOTHO Anti-aging 2.34
bar=donor   line=cohort median 		2.51 24.6%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 14.9%
IL6 Inflammation 1.28
bar=donor   line=cohort median 		1.16 71.5%
TERT Telomere Maintenance 1.56
bar=donor   line=cohort median 		1.51 59.3%
IRS2 Insulin/IGF-1 Signaling 10.59
bar=donor   line=cohort median 		9.81 86.6%
TP53 Tumor Suppression 8.49
bar=donor   line=cohort median 		8.92 7.4%
SHC1 Signal Transduction 9.32
bar=donor   line=cohort median 		9.35 40.0%
ACE Signal Transduction 5.04
bar=donor   line=cohort median 		4.64 84.8%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.0 0
2 B2M 17.0 0
3 EEF1A1 16.9 0
4 MT-CO1 16.4 0
5 ACTB 16.3 0
6 HLA-C 16.2 0
7 HLA-B 16.1 0
8 TXNIP 15.8 0
9 HLA-E 15.7 0
10 MT-RNR1 15.6 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 13.4
bar=donor   line=cohort median 		13.8 14.2 13.4%
2 S100A9 15.1
bar=donor   line=cohort median 		15.3 15.5 19.2%
3 IL1B 7.5
bar=donor   line=cohort median 		9.5 9.3 1.6%
4 CXCL8 12.1
bar=donor   line=cohort median 		10.6 11.4 72.2%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 5.9
bar=donor   line=cohort median 		6.0 6.1 32.1%
6 FCGR3B 14.2
bar=donor   line=cohort median 		14.6 14.7 17.4%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.4
bar=donor   line=cohort median 		14.3 14.3 51.8%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.8
bar=donor   line=cohort median 		10.2 10.4 89.4%
9 CD3E 12.2
bar=donor   line=cohort median 		11.9 12.0 82.6%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 10.8
bar=donor   line=cohort median 		11.0 10.9 37.5%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 12.2
bar=donor   line=cohort median 		11.7 11.7 81.9%
12 GNLY 11.8
bar=donor   line=cohort median 		12.0 12.1 22.8%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.4
bar=donor   line=cohort median 		16.4 16.4 46.8%
17 MT-CO2 15.2
bar=donor   line=cohort median 		15.2 15.3 38.2%
18 MT-ND1 15.0
bar=donor   line=cohort median 		15.0 15.2 22.0%
◂ Previous Donor Back to Donor List Next Donor ▸