GSM8077524

Dataset: gse255685 • Sample: YZ569 • Status: MDD with drug therapy
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Quality Control Metrics

2 Mean expression score Group median: 2 • 25.3%ile (≈ Median)
22,344 Genes with score > 0 Group median: 22,378 • 10.6%ile (↓ Low)
0 Median expression score Group median: 0 • 8.1%ile (↓ Low)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

46.3Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 1.73
bar=donor   line=cohort median 		2.02 6.3%
FOXO3 Insulin/IGF-1 Signaling 9.83
bar=donor   line=cohort median 		9.99 26.7%
CETP Lipid Metabolism 4.94
bar=donor   line=cohort median 		5.05 36.7%
SIRT6 Sirtuin Family 8.28
bar=donor   line=cohort median 		8.34 35.7%
SIRT1 Sirtuin Family 8.73
bar=donor   line=cohort median 		8.72 52.2%
SIRT3 Sirtuin Family 7.73
bar=donor   line=cohort median 		7.49 88.4%
IGF1R Insulin/IGF-1 Signaling 9.92
bar=donor   line=cohort median 		10.21 25.3%
KLOTHO Anti-aging 2.46
bar=donor   line=cohort median 		2.51 45.0%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 73.3%
IL6 Inflammation 1.21
bar=donor   line=cohort median 		1.16 60.8%
TERT Telomere Maintenance 1.87
bar=donor   line=cohort median 		1.51 95.2%
IRS2 Insulin/IGF-1 Signaling 9.68
bar=donor   line=cohort median 		9.81 36.0%
TP53 Tumor Suppression 8.71
bar=donor   line=cohort median 		8.92 28.5%
SHC1 Signal Transduction 9.06
bar=donor   line=cohort median 		9.35 0.9%
ACE Signal Transduction 5.03
bar=donor   line=cohort median 		4.64 84.1%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.7 0
2 B2M 17.3 0
3 EEF1A1 17.0 0
4 ACTB 16.6 0
5 MT-CO1 16.6 0
6 S100A9 16.2 0
7 HLA-B 16.1 0
8 MT-RNR1 16.1 0
9 HLA-C 16.0 0
10 MT-ND4 15.9 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 15.2
bar=donor   line=cohort median 		14.2 14.2 95.9%
2 S100A9 16.2
bar=donor   line=cohort median 		15.4 15.5 87.6%
3 IL1B 8.8
bar=donor   line=cohort median 		9.5 9.3 29.2%
4 CXCL8 11.7
bar=donor   line=cohort median 		10.3 11.4 58.6%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 6.2
bar=donor   line=cohort median 		6.1 6.1 59.3%
6 FCGR3B 11.5
bar=donor   line=cohort median 		14.7 14.7 0.2%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.5
bar=donor   line=cohort median 		14.4 14.3 64.0%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.7
bar=donor   line=cohort median 		10.3 10.4 85.8%
9 CD3E 12.1
bar=donor   line=cohort median 		11.9 12.0 69.7%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 10.4
bar=donor   line=cohort median 		10.9 10.9 10.6%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 11.0
bar=donor   line=cohort median 		11.5 11.7 4.1%
12 GNLY 11.6
bar=donor   line=cohort median 		12.0 12.1 15.6%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.6
bar=donor   line=cohort median 		16.4 16.4 79.0%
17 MT-CO2 15.6
bar=donor   line=cohort median 		15.3 15.3 85.1%
18 MT-ND1 15.5
bar=donor   line=cohort median 		15.2 15.2 80.1%
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