GSM8077526

Dataset: gse255685 • Sample: YZ571 • Status: MDD without drug therapy
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Quality Control Metrics

2 Mean expression score Group median: 2 • 37.5%ile (≈ Median)
22,390 Genes with score > 0 Group median: 22,375 • 67.7%ile (≈ Median)
0 Median expression score Group median: 0 • 43.9%ile (≈ Median)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

59.1Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 1.78
bar=donor   line=cohort median 		2.02 10.9%
FOXO3 Insulin/IGF-1 Signaling 10.03
bar=donor   line=cohort median 		9.99 55.7%
CETP Lipid Metabolism 5.77
bar=donor   line=cohort median 		5.05 97.3%
SIRT6 Sirtuin Family 8.43
bar=donor   line=cohort median 		8.34 66.5%
SIRT1 Sirtuin Family 8.96
bar=donor   line=cohort median 		8.72 90.9%
SIRT3 Sirtuin Family 7.34
bar=donor   line=cohort median 		7.49 22.4%
IGF1R Insulin/IGF-1 Signaling 10.82
bar=donor   line=cohort median 		10.21 98.4%
KLOTHO Anti-aging 2.83
bar=donor   line=cohort median 		2.51 87.6%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 29.2%
IL6 Inflammation 1.15
bar=donor   line=cohort median 		1.16 49.6%
TERT Telomere Maintenance 1.44
bar=donor   line=cohort median 		1.51 33.5%
IRS2 Insulin/IGF-1 Signaling 9.72
bar=donor   line=cohort median 		9.81 39.3%
TP53 Tumor Suppression 9.03
bar=donor   line=cohort median 		8.92 71.2%
SHC1 Signal Transduction 9.37
bar=donor   line=cohort median 		9.35 58.6%
ACE Signal Transduction 4.89
bar=donor   line=cohort median 		4.64 75.8%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.2 0
2 B2M 16.8 0
3 EEF1A1 16.6 0
4 ACTB 16.6 0
5 MT-CO1 16.2 0
6 HLA-C 15.8 0
7 FTL 15.8 0
8 CSF3R 15.7 0
9 HLA-B 15.6 0
10 HLA-E 15.6 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 13.9
bar=donor   line=cohort median 		13.8 14.2 34.9%
2 S100A9 15.3
bar=donor   line=cohort median 		15.3 15.5 34.9%
3 IL1B 9.8
bar=donor   line=cohort median 		9.5 9.3 75.1%
4 CXCL8 10.0
bar=donor   line=cohort median 		10.6 11.4 27.8%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 5.8
bar=donor   line=cohort median 		6.0 6.1 24.6%
6 FCGR3B 14.6
bar=donor   line=cohort median 		14.6 14.7 41.4%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.8
bar=donor   line=cohort median 		14.3 14.3 85.1%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.2
bar=donor   line=cohort median 		10.2 10.4 26.7%
9 CD3E 11.7
bar=donor   line=cohort median 		11.9 12.0 11.3%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 11.0
bar=donor   line=cohort median 		11.0 10.9 65.1%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 11.3
bar=donor   line=cohort median 		11.7 11.7 18.8%
12 GNLY 11.9
bar=donor   line=cohort median 		12.0 12.1 34.2%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.2
bar=donor   line=cohort median 		16.4 16.4 12.7%
17 MT-CO2 15.0
bar=donor   line=cohort median 		15.2 15.3 12.0%
18 MT-ND1 15.0
bar=donor   line=cohort median 		15.0 15.2 22.4%
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