GSM8077527

Dataset: gse255685 • Sample: YZ573 • Status: MDD with drug therapy
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Quality Control Metrics

2 Mean expression score Group median: 2 • 52.5%ile (≈ Median)
22,357 Genes with score > 0 Group median: 22,378 • 23.1%ile (↓ Low)
0 Median expression score Group median: 0 • 38.5%ile (≈ Median)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

47.4Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 2.08
bar=donor   line=cohort median 		2.02 60.8%
FOXO3 Insulin/IGF-1 Signaling 10.17
bar=donor   line=cohort median 		9.99 80.1%
CETP Lipid Metabolism 4.95
bar=donor   line=cohort median 		5.05 38.9%
SIRT6 Sirtuin Family 8.27
bar=donor   line=cohort median 		8.34 33.2%
SIRT1 Sirtuin Family 8.91
bar=donor   line=cohort median 		8.72 84.4%
SIRT3 Sirtuin Family 7.48
bar=donor   line=cohort median 		7.49 47.9%
IGF1R Insulin/IGF-1 Signaling 10.33
bar=donor   line=cohort median 		10.21 61.1%
KLOTHO Anti-aging 2.77
bar=donor   line=cohort median 		2.51 82.6%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 35.7%
IL6 Inflammation 1.08
bar=donor   line=cohort median 		1.16 27.8%
TERT Telomere Maintenance 1.36
bar=donor   line=cohort median 		1.51 16.7%
IRS2 Insulin/IGF-1 Signaling 9.58
bar=donor   line=cohort median 		9.81 27.8%
TP53 Tumor Suppression 9.01
bar=donor   line=cohort median 		8.92 64.0%
SHC1 Signal Transduction 9.29
bar=donor   line=cohort median 		9.35 29.2%
ACE Signal Transduction 4.36
bar=donor   line=cohort median 		4.64 20.6%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.6 0
2 B2M 16.8 0
3 EEF1A1 16.6 0
4 ACTB 16.4 0
5 MT-CO1 16.3 0
6 MT-RNR1 15.9 0
7 HLA-C 15.9 0
8 HLA-B 15.6 0
9 FKBP8 15.6 0
10 MT-ND4 15.6 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 14.4
bar=donor   line=cohort median 		14.2 14.2 65.8%
2 S100A9 15.5
bar=donor   line=cohort median 		15.4 15.5 46.1%
3 IL1B 9.5
bar=donor   line=cohort median 		9.5 9.3 63.6%
4 CXCL8 9.7
bar=donor   line=cohort median 		10.3 11.4 23.8%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 7.3
bar=donor   line=cohort median 		6.1 6.1 91.6%
6 FCGR3B 15.0
bar=donor   line=cohort median 		14.7 14.7 73.3%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.7
bar=donor   line=cohort median 		14.4 14.3 76.9%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.3
bar=donor   line=cohort median 		10.3 10.4 42.1%
9 CD3E 11.9
bar=donor   line=cohort median 		11.9 12.0 30.3%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 10.9
bar=donor   line=cohort median 		10.9 10.9 50.0%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 11.2
bar=donor   line=cohort median 		11.5 11.7 10.2%
12 GNLY 11.8
bar=donor   line=cohort median 		12.0 12.1 23.5%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.3
bar=donor   line=cohort median 		16.4 16.4 28.9%
17 MT-CO2 15.3
bar=donor   line=cohort median 		15.3 15.3 50.7%
18 MT-ND1 15.3
bar=donor   line=cohort median 		15.2 15.2 61.1%
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