GSM8077532

Dataset: gse255685 • Sample: YZ587 • Status: MDD with drug therapy
◂ Prev All Donors Next ▸

Quality Control Metrics

2 Mean expression score Group median: 2 • 56.5%ile (≈ Median)
22,375 Genes with score > 0 Group median: 22,378 • 45.0%ile (≈ Median)
0 Median expression score Group median: 0 • 43.2%ile (≈ Median)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

57.1Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 1.97
bar=donor   line=cohort median 		2.02 41.8%
FOXO3 Insulin/IGF-1 Signaling 10.16
bar=donor   line=cohort median 		9.99 77.2%
CETP Lipid Metabolism 5.10
bar=donor   line=cohort median 		5.05 60.0%
SIRT6 Sirtuin Family 8.43
bar=donor   line=cohort median 		8.34 67.6%
SIRT1 Sirtuin Family 8.64
bar=donor   line=cohort median 		8.72 40.0%
SIRT3 Sirtuin Family 7.47
bar=donor   line=cohort median 		7.49 46.4%
IGF1R Insulin/IGF-1 Signaling 10.51
bar=donor   line=cohort median 		10.21 83.3%
KLOTHO Anti-aging 2.40
bar=donor   line=cohort median 		2.51 33.5%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 51.8%
IL6 Inflammation 1.00
bar=donor   line=cohort median 		1.16 8.8%
TERT Telomere Maintenance 1.61
bar=donor   line=cohort median 		1.51 71.5%
IRS2 Insulin/IGF-1 Signaling 9.79
bar=donor   line=cohort median 		9.81 47.1%
TP53 Tumor Suppression 9.10
bar=donor   line=cohort median 		8.92 80.1%
SHC1 Signal Transduction 9.48
bar=donor   line=cohort median 		9.35 83.7%
ACE Signal Transduction 4.77
bar=donor   line=cohort median 		4.64 62.9%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 18.1 0
2 B2M 17.0 0
3 ACTB 16.7 0
4 MT-CO1 16.6 0
5 EEF1A1 16.5 0
6 MT-RNR1 16.4 0
7 HLA-C 16.1 0
8 MT-ND4 16.0 0
9 FTL 15.9 0
10 HLA-B 15.9 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 14.2
bar=donor   line=cohort median 		14.2 14.2 51.8%
2 S100A9 15.6
bar=donor   line=cohort median 		15.4 15.5 56.5%
3 IL1B 10.1
bar=donor   line=cohort median 		9.5 9.3 89.1%
4 CXCL8 9.9
bar=donor   line=cohort median 		10.3 11.4 26.3%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 5.8
bar=donor   line=cohort median 		6.1 6.1 26.0%
6 FCGR3B 15.2
bar=donor   line=cohort median 		14.7 14.7 84.8%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.4
bar=donor   line=cohort median 		14.4 14.3 54.3%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.0
bar=donor   line=cohort median 		10.3 10.4 13.1%
9 CD3E 11.7
bar=donor   line=cohort median 		11.9 12.0 9.1%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 10.9
bar=donor   line=cohort median 		10.9 10.9 43.9%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 11.6
bar=donor   line=cohort median 		11.5 11.7 43.5%
12 GNLY 11.8
bar=donor   line=cohort median 		12.0 12.1 27.1%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.6
bar=donor   line=cohort median 		16.4 16.4 80.1%
17 MT-CO2 15.7
bar=donor   line=cohort median 		15.3 15.3 85.8%
18 MT-ND1 15.7
bar=donor   line=cohort median 		15.2 15.2 93.4%
◂ Previous Donor Back to Donor List Next Donor ▸