GSM8077541

Dataset: gse255685 • Sample: YZ608 • Status: MDD without drug therapy
◂ Prev All Donors Next ▸

Quality Control Metrics

2 Mean expression score Group median: 2 • 28.5%ile (≈ Median)
22,372 Genes with score > 0 Group median: 22,375 • 41.4%ile (≈ Median)
0 Median expression score Group median: 0 • 15.2%ile (↓ Low)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

48.7Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 1.78
bar=donor   line=cohort median 		2.02 10.2%
FOXO3 Insulin/IGF-1 Signaling 9.73
bar=donor   line=cohort median 		9.99 17.7%
CETP Lipid Metabolism 5.95
bar=donor   line=cohort median 		5.05 99.1%
SIRT6 Sirtuin Family 8.28
bar=donor   line=cohort median 		8.34 34.6%
SIRT1 Sirtuin Family 8.92
bar=donor   line=cohort median 		8.72 86.9%
SIRT3 Sirtuin Family 7.47
bar=donor   line=cohort median 		7.49 45.7%
IGF1R Insulin/IGF-1 Signaling 10.08
bar=donor   line=cohort median 		10.21 36.7%
KLOTHO Anti-aging 3.17
bar=donor   line=cohort median 		2.51 99.5%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 27.1%
IL6 Inflammation 1.15
bar=donor   line=cohort median 		1.16 48.6%
TERT Telomere Maintenance 1.36
bar=donor   line=cohort median 		1.51 14.9%
IRS2 Insulin/IGF-1 Signaling 9.34
bar=donor   line=cohort median 		9.81 11.7%
TP53 Tumor Suppression 9.29
bar=donor   line=cohort median 		8.92 97.0%
SHC1 Signal Transduction 9.36
bar=donor   line=cohort median 		9.35 56.5%
ACE Signal Transduction 4.58
bar=donor   line=cohort median 		4.64 45.0%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.3 0
2 EEF1A1 16.9 0
3 B2M 16.7 0
4 MT-CO1 16.5 0
5 ACTB 16.4 0
6 MT-RNR1 15.8 0
7 HLA-B 15.6 0
8 HLA-C 15.6 0
9 MT-ND4 15.6 0
10 FTL 15.5 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 13.3
bar=donor   line=cohort median 		13.8 14.2 11.3%
2 S100A9 14.9
bar=donor   line=cohort median 		15.3 15.5 11.3%
3 IL1B 9.5
bar=donor   line=cohort median 		9.5 9.3 59.7%
4 CXCL8 9.3
bar=donor   line=cohort median 		10.6 11.4 14.9%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 5.7
bar=donor   line=cohort median 		6.0 6.1 17.0%
6 FCGR3B 14.8
bar=donor   line=cohort median 		14.6 14.7 62.9%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.4
bar=donor   line=cohort median 		14.3 14.3 55.4%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.3
bar=donor   line=cohort median 		10.2 10.4 44.3%
9 CD3E 11.9
bar=donor   line=cohort median 		11.9 12.0 44.6%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 11.5
bar=donor   line=cohort median 		11.0 10.9 95.9%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 11.1
bar=donor   line=cohort median 		11.7 11.7 7.0%
12 GNLY 11.4
bar=donor   line=cohort median 		12.0 12.1 8.8%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.5
bar=donor   line=cohort median 		16.4 16.4 70.1%
17 MT-CO2 15.1
bar=donor   line=cohort median 		15.2 15.3 22.0%
18 MT-ND1 14.9
bar=donor   line=cohort median 		15.0 15.2 17.0%
◂ Previous Donor Back to Donor List Next Donor ▸