GSM8077544

Dataset: gse255685 • Sample: YZ613 • Status: MDD with drug therapy
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Quality Control Metrics

2 Mean expression score Group median: 2 • 50.7%ile (≈ Median)
22,373 Genes with score > 0 Group median: 22,378 • 42.8%ile (≈ Median)
0 Median expression score Group median: 0 • 54.7%ile (≈ Median)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

38.3Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 1.72
bar=donor   line=cohort median 		2.02 3.8%
FOXO3 Insulin/IGF-1 Signaling 9.74
bar=donor   line=cohort median 		9.99 19.2%
CETP Lipid Metabolism 5.59
bar=donor   line=cohort median 		5.05 94.1%
SIRT6 Sirtuin Family 8.12
bar=donor   line=cohort median 		8.34 7.4%
SIRT1 Sirtuin Family 8.81
bar=donor   line=cohort median 		8.72 69.4%
SIRT3 Sirtuin Family 7.32
bar=donor   line=cohort median 		7.49 20.3%
IGF1R Insulin/IGF-1 Signaling 9.68
bar=donor   line=cohort median 		10.21 9.1%
KLOTHO Anti-aging 2.50
bar=donor   line=cohort median 		2.51 49.3%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 64.0%
IL6 Inflammation 1.19
bar=donor   line=cohort median 		1.16 58.6%
TERT Telomere Maintenance 1.29
bar=donor   line=cohort median 		1.51 5.9%
IRS2 Insulin/IGF-1 Signaling 9.07
bar=donor   line=cohort median 		9.81 2.0%
TP53 Tumor Suppression 9.10
bar=donor   line=cohort median 		8.92 79.0%
SHC1 Signal Transduction 9.24
bar=donor   line=cohort median 		9.35 15.6%
ACE Signal Transduction 4.89
bar=donor   line=cohort median 		4.64 76.5%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.4 0
2 B2M 16.9 0
3 EEF1A1 16.4 0
4 MT-CO1 16.4 0
5 ACTB 16.3 0
6 HLA-C 16.0 0
7 MT-RNR1 16.0 0
8 FTL 15.7 0
9 HLA-E 15.6 0
10 HLA-B 15.5 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 13.4
bar=donor   line=cohort median 		14.2 14.2 14.2%
2 S100A9 15.1
bar=donor   line=cohort median 		15.4 15.5 18.5%
3 IL1B 9.3
bar=donor   line=cohort median 		9.5 9.3 46.8%
4 CXCL8 9.6
bar=donor   line=cohort median 		10.3 11.4 20.6%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 5.8
bar=donor   line=cohort median 		6.1 6.1 28.9%
6 FCGR3B 15.0
bar=donor   line=cohort median 		14.7 14.7 70.4%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 13.8
bar=donor   line=cohort median 		14.4 14.3 12.0%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.2
bar=donor   line=cohort median 		10.3 10.4 31.0%
9 CD3E 11.8
bar=donor   line=cohort median 		11.9 12.0 19.2%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 11.5
bar=donor   line=cohort median 		10.9 10.9 98.0%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 11.9
bar=donor   line=cohort median 		11.5 11.7 65.8%
12 GNLY 12.6
bar=donor   line=cohort median 		12.0 12.1 80.1%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.4
bar=donor   line=cohort median 		16.4 16.4 42.8%
17 MT-CO2 15.1
bar=donor   line=cohort median 		15.3 15.3 17.7%
18 MT-ND1 15.0
bar=donor   line=cohort median 		15.2 15.2 25.6%
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