GSM8077564

Dataset: gse255685 • Sample: YZ664 • Status: MDD without drug therapy
◂ Prev All Donors Next ▸

Quality Control Metrics

2 Mean expression score Group median: 2 • 77.6%ile (↑ High)
22,388 Genes with score > 0 Group median: 22,375 • 65.2%ile (≈ Median)
0 Median expression score Group median: 0 • 81.2%ile (↑ High)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

46.2Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 1.94
bar=donor   line=cohort median 		2.02 37.1%
FOXO3 Insulin/IGF-1 Signaling 10.07
bar=donor   line=cohort median 		9.99 61.8%
CETP Lipid Metabolism 4.83
bar=donor   line=cohort median 		5.05 23.1%
SIRT6 Sirtuin Family 8.37
bar=donor   line=cohort median 		8.34 59.3%
SIRT1 Sirtuin Family 8.73
bar=donor   line=cohort median 		8.72 53.2%
SIRT3 Sirtuin Family 7.45
bar=donor   line=cohort median 		7.49 41.4%
IGF1R Insulin/IGF-1 Signaling 10.39
bar=donor   line=cohort median 		10.21 71.2%
KLOTHO Anti-aging 2.23
bar=donor   line=cohort median 		2.51 11.7%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 30.3%
IL6 Inflammation 0.99
bar=donor   line=cohort median 		1.16 4.1%
TERT Telomere Maintenance 1.51
bar=donor   line=cohort median 		1.51 49.6%
IRS2 Insulin/IGF-1 Signaling 11.01
bar=donor   line=cohort median 		9.81 97.0%
TP53 Tumor Suppression 8.75
bar=donor   line=cohort median 		8.92 32.4%
SHC1 Signal Transduction 9.33
bar=donor   line=cohort median 		9.35 41.8%
ACE Signal Transduction 4.94
bar=donor   line=cohort median 		4.64 79.0%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.7 0
2 EEF1A1 16.8 0
3 B2M 16.8 0
4 MT-CO1 16.6 0
5 ACTB 16.5 0
6 MT-RNR1 16.3 0
7 HLA-C 16.0 0
8 TXNIP 15.8 0
9 MT-ND4 15.8 0
10 HLA-E 15.7 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 13.7
bar=donor   line=cohort median 		13.8 14.2 22.4%
2 S100A9 15.3
bar=donor   line=cohort median 		15.3 15.5 29.9%
3 IL1B 8.5
bar=donor   line=cohort median 		9.5 9.3 17.4%
4 CXCL8 12.4
bar=donor   line=cohort median 		10.6 11.4 82.6%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 7.9
bar=donor   line=cohort median 		6.0 6.1 97.0%
6 FCGR3B 15.0
bar=donor   line=cohort median 		14.6 14.7 71.9%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 13.8
bar=donor   line=cohort median 		14.3 14.3 10.2%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.3
bar=donor   line=cohort median 		10.2 10.4 40.7%
9 CD3E 12.0
bar=donor   line=cohort median 		11.9 12.0 51.8%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 11.0
bar=donor   line=cohort median 		11.0 10.9 62.2%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 11.6
bar=donor   line=cohort median 		11.7 11.7 41.4%
12 GNLY 12.1
bar=donor   line=cohort median 		12.0 12.1 47.1%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.6
bar=donor   line=cohort median 		16.4 16.4 85.8%
17 MT-CO2 15.4
bar=donor   line=cohort median 		15.2 15.3 54.3%
18 MT-ND1 15.3
bar=donor   line=cohort median 		15.0 15.2 66.8%
◂ Previous Donor Back to Donor List Next Donor ▸