GSM8077565

Dataset: gse255685 • Sample: YZ666 • Status: MDD with drug therapy
◂ Prev All Donors Next ▸

Quality Control Metrics

2 Mean expression score Group median: 2 • 61.5%ile (≈ Median)
22,378 Genes with score > 0 Group median: 22,378 • 50.0%ile (≈ Median)
0 Median expression score Group median: 0 • 74.4%ile (≈ Median)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

45.4Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 1.87
bar=donor   line=cohort median 		2.02 24.9%
FOXO3 Insulin/IGF-1 Signaling 9.81
bar=donor   line=cohort median 		9.99 26.0%
CETP Lipid Metabolism 4.74
bar=donor   line=cohort median 		5.05 16.0%
SIRT6 Sirtuin Family 8.20
bar=donor   line=cohort median 		8.34 18.5%
SIRT1 Sirtuin Family 8.76
bar=donor   line=cohort median 		8.72 59.0%
SIRT3 Sirtuin Family 7.62
bar=donor   line=cohort median 		7.49 74.4%
IGF1R Insulin/IGF-1 Signaling 10.53
bar=donor   line=cohort median 		10.21 85.1%
KLOTHO Anti-aging 2.37
bar=donor   line=cohort median 		2.51 31.0%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 34.2%
IL6 Inflammation 1.31
bar=donor   line=cohort median 		1.16 77.6%
TERT Telomere Maintenance 1.44
bar=donor   line=cohort median 		1.51 35.0%
IRS2 Insulin/IGF-1 Signaling 9.45
bar=donor   line=cohort median 		9.81 17.4%
TP53 Tumor Suppression 9.02
bar=donor   line=cohort median 		8.92 69.0%
SHC1 Signal Transduction 9.29
bar=donor   line=cohort median 		9.35 26.7%
ACE Signal Transduction 5.05
bar=donor   line=cohort median 		4.64 85.8%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.4 0
2 B2M 16.8 0
3 EEF1A1 16.7 0
4 ACTB 16.3 0
5 MT-CO1 16.2 0
6 MT-RNR1 15.8 0
7 HLA-C 15.7 0
8 S100A9 15.5 0
9 HLA-B 15.5 0
10 HLA-E 15.5 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 14.4
bar=donor   line=cohort median 		14.2 14.2 65.1%
2 S100A9 15.5
bar=donor   line=cohort median 		15.4 15.5 51.8%
3 IL1B 9.9
bar=donor   line=cohort median 		9.5 9.3 80.5%
4 CXCL8 10.1
bar=donor   line=cohort median 		10.3 11.4 29.2%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 5.3
bar=donor   line=cohort median 		6.1 6.1 2.3%
6 FCGR3B 15.0
bar=donor   line=cohort median 		14.7 14.7 70.8%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.5
bar=donor   line=cohort median 		14.4 14.3 65.1%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.4
bar=donor   line=cohort median 		10.3 10.4 59.7%
9 CD3E 12.0
bar=donor   line=cohort median 		11.9 12.0 47.5%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 11.3
bar=donor   line=cohort median 		10.9 10.9 91.9%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 11.3
bar=donor   line=cohort median 		11.5 11.7 16.7%
12 GNLY 11.5
bar=donor   line=cohort median 		12.0 12.1 11.6%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.2
bar=donor   line=cohort median 		16.4 16.4 10.9%
17 MT-CO2 15.1
bar=donor   line=cohort median 		15.3 15.3 26.0%
18 MT-ND1 15.1
bar=donor   line=cohort median 		15.2 15.2 30.6%
◂ Previous Donor Back to Donor List Next Donor ▸