GSM8077570

Dataset: gse255685 • Sample: YZ678 • Status: MDD without drug therapy
◂ Prev All Donors Next ▸

Quality Control Metrics

2 Mean expression score Group median: 2 • 66.1%ile (≈ Median)
22,380 Genes with score > 0 Group median: 22,375 • 53.8%ile (≈ Median)
0 Median expression score Group median: 0 • 47.5%ile (≈ Median)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

45.7Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 2.11
bar=donor   line=cohort median 		2.02 66.1%
FOXO3 Insulin/IGF-1 Signaling 10.08
bar=donor   line=cohort median 		9.99 62.5%
CETP Lipid Metabolism 4.97
bar=donor   line=cohort median 		5.05 41.4%
SIRT6 Sirtuin Family 8.20
bar=donor   line=cohort median 		8.34 18.8%
SIRT1 Sirtuin Family 8.55
bar=donor   line=cohort median 		8.72 25.6%
SIRT3 Sirtuin Family 7.23
bar=donor   line=cohort median 		7.49 8.1%
IGF1R Insulin/IGF-1 Signaling 10.06
bar=donor   line=cohort median 		10.21 35.7%
KLOTHO Anti-aging 2.26
bar=donor   line=cohort median 		2.51 13.1%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 52.9%
IL6 Inflammation 1.26
bar=donor   line=cohort median 		1.16 68.6%
TERT Telomere Maintenance 1.61
bar=donor   line=cohort median 		1.51 72.6%
IRS2 Insulin/IGF-1 Signaling 9.93
bar=donor   line=cohort median 		9.81 60.4%
TP53 Tumor Suppression 8.60
bar=donor   line=cohort median 		8.92 17.0%
SHC1 Signal Transduction 9.36
bar=donor   line=cohort median 		9.35 52.9%
ACE Signal Transduction 5.08
bar=donor   line=cohort median 		4.64 89.1%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.4 0
2 B2M 17.0 0
3 EEF1A1 16.8 0
4 ACTB 16.5 0
5 MT-CO1 16.5 0
6 HLA-C 16.1 0
7 MT-RNR1 16.1 0
8 HLA-B 15.9 0
9 HLA-E 15.8 0
10 FTL 15.7 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 14.4
bar=donor   line=cohort median 		13.8 14.2 62.5%
2 S100A9 15.6
bar=donor   line=cohort median 		15.3 15.5 56.8%
3 IL1B 9.5
bar=donor   line=cohort median 		9.5 9.3 58.2%
4 CXCL8 12.8
bar=donor   line=cohort median 		10.6 11.4 89.8%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 7.0
bar=donor   line=cohort median 		6.0 6.1 87.3%
6 FCGR3B 14.5
bar=donor   line=cohort median 		14.6 14.7 33.9%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 15.1
bar=donor   line=cohort median 		14.3 14.3 97.3%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.4
bar=donor   line=cohort median 		10.2 10.4 55.4%
9 CD3E 11.8
bar=donor   line=cohort median 		11.9 12.0 18.1%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 11.4
bar=donor   line=cohort median 		11.0 10.9 92.7%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 11.5
bar=donor   line=cohort median 		11.7 11.7 40.0%
12 GNLY 11.6
bar=donor   line=cohort median 		12.0 12.1 14.2%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.5
bar=donor   line=cohort median 		16.4 16.4 60.8%
17 MT-CO2 15.3
bar=donor   line=cohort median 		15.2 15.3 39.2%
18 MT-ND1 15.3
bar=donor   line=cohort median 		15.0 15.2 59.0%
◂ Previous Donor Back to Donor List Next Donor ▸