GSM8077574

Dataset: gse255685 • Sample: YZ687 • Status: MDD without drug therapy
◂ Prev All Donors Next ▸

Quality Control Metrics

2 Mean expression score Group median: 2 • 35.7%ile (≈ Median)
22,361 Genes with score > 0 Group median: 22,375 • 27.4%ile (≈ Median)
0 Median expression score Group median: 0 • 54.3%ile (≈ Median)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

41.6Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 1.70
bar=donor   line=cohort median 		2.02 1.6%
FOXO3 Insulin/IGF-1 Signaling 10.12
bar=donor   line=cohort median 		9.99 71.5%
CETP Lipid Metabolism 5.07
bar=donor   line=cohort median 		5.05 54.3%
SIRT6 Sirtuin Family 8.09
bar=donor   line=cohort median 		8.34 4.1%
SIRT1 Sirtuin Family 8.61
bar=donor   line=cohort median 		8.72 37.1%
SIRT3 Sirtuin Family 7.30
bar=donor   line=cohort median 		7.49 16.3%
IGF1R Insulin/IGF-1 Signaling 10.32
bar=donor   line=cohort median 		10.21 59.3%
KLOTHO Anti-aging 2.37
bar=donor   line=cohort median 		2.51 30.7%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 33.9%
IL6 Inflammation 1.31
bar=donor   line=cohort median 		1.16 77.2%
TERT Telomere Maintenance 1.44
bar=donor   line=cohort median 		1.51 34.6%
IRS2 Insulin/IGF-1 Signaling 10.22
bar=donor   line=cohort median 		9.81 72.9%
TP53 Tumor Suppression 8.65
bar=donor   line=cohort median 		8.92 19.9%
SHC1 Signal Transduction 9.30
bar=donor   line=cohort median 		9.35 32.4%
ACE Signal Transduction 4.94
bar=donor   line=cohort median 		4.64 78.7%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.5 0
2 B2M 17.1 0
3 EEF1A1 16.9 0
4 MT-CO1 16.6 0
5 ACTB 16.5 0
6 HLA-C 16.3 0
7 MT-RNR1 15.9 0
8 HLA-E 15.8 0
9 FTL 15.8 0
10 MT-ND4 15.8 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 14.2
bar=donor   line=cohort median 		13.8 14.2 48.9%
2 S100A9 15.6
bar=donor   line=cohort median 		15.3 15.5 53.6%
3 IL1B 8.9
bar=donor   line=cohort median 		9.5 9.3 32.1%
4 CXCL8 11.4
bar=donor   line=cohort median 		10.6 11.4 51.1%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 5.7
bar=donor   line=cohort median 		6.0 6.1 19.2%
6 FCGR3B 14.1
bar=donor   line=cohort median 		14.6 14.7 10.9%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.5
bar=donor   line=cohort median 		14.3 14.3 63.3%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.3
bar=donor   line=cohort median 		10.2 10.4 45.3%
9 CD3E 11.9
bar=donor   line=cohort median 		11.9 12.0 36.4%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 11.2
bar=donor   line=cohort median 		11.0 10.9 80.8%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 11.4
bar=donor   line=cohort median 		11.7 11.7 23.5%
12 GNLY 11.5
bar=donor   line=cohort median 		12.0 12.1 10.6%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.6
bar=donor   line=cohort median 		16.4 16.4 86.6%
17 MT-CO2 15.5
bar=donor   line=cohort median 		15.2 15.3 73.7%
18 MT-ND1 15.2
bar=donor   line=cohort median 		15.0 15.2 51.1%
◂ Previous Donor Back to Donor List Next Donor ▸