GSM8077582

Dataset: gse255685 • Sample: YZ798 • Status: MDD without drug therapy
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Quality Control Metrics

2 Mean expression score Group median: 2 • 16.7%ile (↓ Low)
22,324 Genes with score > 0 Group median: 22,375 • 2.0%ile (↓ Low)
0 Median expression score Group median: 0 • 1.6%ile (↓ Low)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

49.9Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 1.80
bar=donor   line=cohort median 		2.02 15.6%
FOXO3 Insulin/IGF-1 Signaling 10.06
bar=donor   line=cohort median 		9.99 59.3%
CETP Lipid Metabolism 4.94
bar=donor   line=cohort median 		5.05 37.1%
SIRT6 Sirtuin Family 8.40
bar=donor   line=cohort median 		8.34 63.3%
SIRT1 Sirtuin Family 8.84
bar=donor   line=cohort median 		8.72 74.7%
SIRT3 Sirtuin Family 7.17
bar=donor   line=cohort median 		7.49 6.3%
IGF1R Insulin/IGF-1 Signaling 10.47
bar=donor   line=cohort median 		10.21 79.4%
KLOTHO Anti-aging 2.70
bar=donor   line=cohort median 		2.51 76.2%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 51.4%
IL6 Inflammation 1.00
bar=donor   line=cohort median 		1.16 8.4%
TERT Telomere Maintenance 1.46
bar=donor   line=cohort median 		1.51 40.7%
IRS2 Insulin/IGF-1 Signaling 9.82
bar=donor   line=cohort median 		9.81 50.4%
TP53 Tumor Suppression 9.11
bar=donor   line=cohort median 		8.92 80.8%
SHC1 Signal Transduction 9.38
bar=donor   line=cohort median 		9.35 61.8%
ACE Signal Transduction 4.57
bar=donor   line=cohort median 		4.64 43.2%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.5 0
2 B2M 17.2 0
3 ACTB 16.8 0
4 EEF1A1 16.7 0
5 HLA-C 16.6 0
6 MT-CO1 16.4 0
7 MT-RNR1 16.2 0
8 HLA-B 16.0 0
9 FTL 16.0 0
10 S100A9 15.9 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 14.4
bar=donor   line=cohort median 		13.8 14.2 67.2%
2 S100A9 15.9
bar=donor   line=cohort median 		15.3 15.5 77.6%
3 IL1B 10.5
bar=donor   line=cohort median 		9.5 9.3 98.4%
4 CXCL8 11.4
bar=donor   line=cohort median 		10.6 11.4 50.7%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 6.8
bar=donor   line=cohort median 		6.0 6.1 84.1%
6 FCGR3B 15.2
bar=donor   line=cohort median 		14.6 14.7 83.3%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.3
bar=donor   line=cohort median 		14.3 14.3 49.3%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.4
bar=donor   line=cohort median 		10.2 10.4 52.5%
9 CD3E 11.9
bar=donor   line=cohort median 		11.9 12.0 38.9%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 10.9
bar=donor   line=cohort median 		11.0 10.9 47.1%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 11.8
bar=donor   line=cohort median 		11.7 11.7 54.7%
12 GNLY 11.9
bar=donor   line=cohort median 		12.0 12.1 33.5%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.4
bar=donor   line=cohort median 		16.4 16.4 49.6%
17 MT-CO2 15.3
bar=donor   line=cohort median 		15.2 15.3 51.4%
18 MT-ND1 15.1
bar=donor   line=cohort median 		15.0 15.2 34.9%
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