GSM8077584

Dataset: gse255685 • Sample: YZ801 • Status: MDD without drug therapy
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Quality Control Metrics

2 Mean expression score Group median: 2 • 48.2%ile (≈ Median)
22,371 Genes with score > 0 Group median: 22,375 • 40.3%ile (≈ Median)
0 Median expression score Group median: 0 • 71.1%ile (≈ Median)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

54.6Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 1.89
bar=donor   line=cohort median 		2.02 29.9%
FOXO3 Insulin/IGF-1 Signaling 10.10
bar=donor   line=cohort median 		9.99 67.6%
CETP Lipid Metabolism 4.97
bar=donor   line=cohort median 		5.05 42.1%
SIRT6 Sirtuin Family 8.32
bar=donor   line=cohort median 		8.34 43.9%
SIRT1 Sirtuin Family 9.09
bar=donor   line=cohort median 		8.72 99.1%
SIRT3 Sirtuin Family 7.35
bar=donor   line=cohort median 		7.49 25.3%
IGF1R Insulin/IGF-1 Signaling 10.48
bar=donor   line=cohort median 		10.21 80.8%
KLOTHO Anti-aging 2.86
bar=donor   line=cohort median 		2.51 88.4%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 9.5%
IL6 Inflammation 1.05
bar=donor   line=cohort median 		1.16 19.9%
TERT Telomere Maintenance 1.75
bar=donor   line=cohort median 		1.51 88.4%
IRS2 Insulin/IGF-1 Signaling 9.85
bar=donor   line=cohort median 		9.81 52.9%
TP53 Tumor Suppression 9.04
bar=donor   line=cohort median 		8.92 72.2%
SHC1 Signal Transduction 9.33
bar=donor   line=cohort median 		9.35 42.1%
ACE Signal Transduction 4.70
bar=donor   line=cohort median 		4.64 56.5%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.3 0
2 B2M 16.8 0
3 EEF1A1 16.7 0
4 ACTB 16.4 0
5 MT-CO1 16.2 0
6 HLA-B 15.9 0
7 MT-RNR1 15.7 0
8 HLA-C 15.6 0
9 HLA-E 15.6 0
10 FTL 15.5 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 13.7
bar=donor   line=cohort median 		13.8 14.2 22.0%
2 S100A9 15.3
bar=donor   line=cohort median 		15.3 15.5 30.6%
3 IL1B 9.4
bar=donor   line=cohort median 		9.5 9.3 55.0%
4 CXCL8 11.6
bar=donor   line=cohort median 		10.6 11.4 57.9%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 5.6
bar=donor   line=cohort median 		6.0 6.1 10.2%
6 FCGR3B 14.7
bar=donor   line=cohort median 		14.6 14.7 54.7%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.7
bar=donor   line=cohort median 		14.3 14.3 82.6%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.0
bar=donor   line=cohort median 		10.2 10.4 15.2%
9 CD3E 11.7
bar=donor   line=cohort median 		11.9 12.0 10.9%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 11.4
bar=donor   line=cohort median 		11.0 10.9 94.8%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 11.2
bar=donor   line=cohort median 		11.7 11.7 13.1%
12 GNLY 11.4
bar=donor   line=cohort median 		12.0 12.1 6.3%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.2
bar=donor   line=cohort median 		16.4 16.4 9.9%
17 MT-CO2 15.0
bar=donor   line=cohort median 		15.2 15.3 10.9%
18 MT-ND1 14.9
bar=donor   line=cohort median 		15.0 15.2 12.0%
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