GSM8077590

Dataset: gse255685 • Sample: YZ817 • Status: MDD with drug therapy
◂ Prev All Donors Next ▸

Quality Control Metrics

2 Mean expression score Group median: 2 • 66.8%ile (≈ Median)
22,402 Genes with score > 0 Group median: 22,378 • 74.9%ile (≈ Median)
0 Median expression score Group median: 0 • 53.6%ile (≈ Median)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

51.7Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 1.80
bar=donor   line=cohort median 		2.02 14.2%
FOXO3 Insulin/IGF-1 Signaling 10.08
bar=donor   line=cohort median 		9.99 64.7%
CETP Lipid Metabolism 5.25
bar=donor   line=cohort median 		5.05 76.9%
SIRT6 Sirtuin Family 8.32
bar=donor   line=cohort median 		8.34 45.3%
SIRT1 Sirtuin Family 8.92
bar=donor   line=cohort median 		8.72 88.0%
SIRT3 Sirtuin Family 7.51
bar=donor   line=cohort median 		7.49 53.2%
IGF1R Insulin/IGF-1 Signaling 10.33
bar=donor   line=cohort median 		10.21 60.8%
KLOTHO Anti-aging 3.05
bar=donor   line=cohort median 		2.51 97.0%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 46.4%
IL6 Inflammation 1.09
bar=donor   line=cohort median 		1.16 30.7%
TERT Telomere Maintenance 1.37
bar=donor   line=cohort median 		1.51 19.5%
IRS2 Insulin/IGF-1 Signaling 10.01
bar=donor   line=cohort median 		9.81 65.1%
TP53 Tumor Suppression 8.76
bar=donor   line=cohort median 		8.92 33.2%
SHC1 Signal Transduction 9.31
bar=donor   line=cohort median 		9.35 38.9%
ACE Signal Transduction 4.56
bar=donor   line=cohort median 		4.64 42.5%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.6 0
2 B2M 17.0 0
3 EEF1A1 16.6 0
4 ACTB 16.4 0
5 MT-CO1 16.3 0
6 HLA-C 16.3 0
7 MT-RNR1 16.1 0
8 FKBP8 15.9 0
9 FTL 15.8 0
10 HLA-B 15.8 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 13.9
bar=donor   line=cohort median 		14.2 14.2 35.3%
2 S100A9 15.5
bar=donor   line=cohort median 		15.4 15.5 50.4%
3 IL1B 9.7
bar=donor   line=cohort median 		9.5 9.3 74.4%
4 CXCL8 12.3
bar=donor   line=cohort median 		10.3 11.4 79.7%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 6.0
bar=donor   line=cohort median 		6.1 6.1 42.1%
6 FCGR3B 15.1
bar=donor   line=cohort median 		14.7 14.7 77.6%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.6
bar=donor   line=cohort median 		14.4 14.3 69.4%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.2
bar=donor   line=cohort median 		10.3 10.4 25.6%
9 CD3E 11.8
bar=donor   line=cohort median 		11.9 12.0 25.6%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 10.8
bar=donor   line=cohort median 		10.9 10.9 36.4%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 11.5
bar=donor   line=cohort median 		11.5 11.7 32.8%
12 GNLY 11.4
bar=donor   line=cohort median 		12.0 12.1 4.1%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.3
bar=donor   line=cohort median 		16.4 16.4 21.3%
17 MT-CO2 15.1
bar=donor   line=cohort median 		15.3 15.3 23.1%
18 MT-ND1 14.9
bar=donor   line=cohort median 		15.2 15.2 14.2%
◂ Previous Donor Back to Donor List Next Donor ▸