GSM8077597

Dataset: gse255685 • Sample: YZ832 • Status: MDD without drug therapy
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Quality Control Metrics

2 Mean expression score Group median: 2 • 60.4%ile (≈ Median)
22,375 Genes with score > 0 Group median: 22,375 • 45.0%ile (≈ Median)
0 Median expression score Group median: 0 • 42.1%ile (≈ Median)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

48.3Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 1.82
bar=donor   line=cohort median 		2.02 17.7%
FOXO3 Insulin/IGF-1 Signaling 9.73
bar=donor   line=cohort median 		9.99 17.4%
CETP Lipid Metabolism 4.99
bar=donor   line=cohort median 		5.05 42.8%
SIRT6 Sirtuin Family 8.29
bar=donor   line=cohort median 		8.34 37.5%
SIRT1 Sirtuin Family 8.77
bar=donor   line=cohort median 		8.72 59.7%
SIRT3 Sirtuin Family 7.35
bar=donor   line=cohort median 		7.49 25.6%
IGF1R Insulin/IGF-1 Signaling 10.19
bar=donor   line=cohort median 		10.21 47.9%
KLOTHO Anti-aging 2.69
bar=donor   line=cohort median 		2.51 75.5%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 62.5%
IL6 Inflammation 1.28
bar=donor   line=cohort median 		1.16 71.2%
TERT Telomere Maintenance 1.39
bar=donor   line=cohort median 		1.51 23.5%
IRS2 Insulin/IGF-1 Signaling 9.71
bar=donor   line=cohort median 		9.81 38.9%
TP53 Tumor Suppression 8.95
bar=donor   line=cohort median 		8.92 55.0%
SHC1 Signal Transduction 9.35
bar=donor   line=cohort median 		9.35 49.3%
ACE Signal Transduction 5.58
bar=donor   line=cohort median 		4.64 99.5%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.8 0
2 B2M 16.9 0
3 EEF1A1 16.8 0
4 MT-CO1 16.8 0
5 MT-RNR1 16.5 0
6 ACTB 16.4 0
7 HLA-C 16.0 0
8 MT-ND4 15.9 0
9 FTL 15.8 0
10 MT-CO3 15.7 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 13.9
bar=donor   line=cohort median 		13.8 14.2 34.6%
2 S100A9 15.3
bar=donor   line=cohort median 		15.3 15.5 35.7%
3 IL1B 10.2
bar=donor   line=cohort median 		9.5 9.3 92.3%
4 CXCL8 12.0
bar=donor   line=cohort median 		10.6 11.4 69.7%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 5.7
bar=donor   line=cohort median 		6.0 6.1 17.7%
6 FCGR3B 13.9
bar=donor   line=cohort median 		14.6 14.7 7.0%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 13.8
bar=donor   line=cohort median 		14.3 14.3 10.6%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.4
bar=donor   line=cohort median 		10.2 10.4 53.2%
9 CD3E 12.1
bar=donor   line=cohort median 		11.9 12.0 67.6%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 11.5
bar=donor   line=cohort median 		11.0 10.9 95.5%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 11.4
bar=donor   line=cohort median 		11.7 11.7 29.6%
12 GNLY 12.2
bar=donor   line=cohort median 		12.0 12.1 52.9%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.8
bar=donor   line=cohort median 		16.4 16.4 94.1%
17 MT-CO2 15.5
bar=donor   line=cohort median 		15.2 15.3 78.3%
18 MT-ND1 15.5
bar=donor   line=cohort median 		15.0 15.2 85.5%
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