GSM8077598

Dataset: gse255685 • Sample: YZ834 • Status: MDD without drug therapy
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Quality Control Metrics

2 Mean expression score Group median: 2 • 32.4%ile (≈ Median)
22,332 Genes with score > 0 Group median: 22,375 • 6.3%ile (↓ Low)
0 Median expression score Group median: 0 • 2.3%ile (↓ Low)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

57.0Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 1.92
bar=donor   line=cohort median 		2.02 35.3%
FOXO3 Insulin/IGF-1 Signaling 9.73
bar=donor   line=cohort median 		9.99 16.7%
CETP Lipid Metabolism 5.88
bar=donor   line=cohort median 		5.05 98.4%
SIRT6 Sirtuin Family 8.57
bar=donor   line=cohort median 		8.34 84.8%
SIRT1 Sirtuin Family 8.76
bar=donor   line=cohort median 		8.72 58.6%
SIRT3 Sirtuin Family 6.94
bar=donor   line=cohort median 		7.49 0.5%
IGF1R Insulin/IGF-1 Signaling 10.43
bar=donor   line=cohort median 		10.21 74.4%
KLOTHO Anti-aging 2.68
bar=donor   line=cohort median 		2.51 73.3%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 23.8%
IL6 Inflammation 1.22
bar=donor   line=cohort median 		1.16 62.9%
TERT Telomere Maintenance 1.90
bar=donor   line=cohort median 		1.51 96.2%
IRS2 Insulin/IGF-1 Signaling 10.02
bar=donor   line=cohort median 		9.81 65.4%
TP53 Tumor Suppression 9.07
bar=donor   line=cohort median 		8.92 74.7%
SHC1 Signal Transduction 9.51
bar=donor   line=cohort median 		9.35 88.4%
ACE Signal Transduction 3.91
bar=donor   line=cohort median 		4.64 1.3%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.3 0
2 B2M 17.3 0
3 ACTB 16.7 0
4 EEF1A1 16.6 0
5 HLA-C 16.6 0
6 HLA-B 16.4 0
7 MT-CO1 16.2 0
8 HLA-E 16.1 0
9 S100A9 16.0 0
10 MT-RNR1 15.9 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 14.5
bar=donor   line=cohort median 		13.8 14.2 69.4%
2 S100A9 16.0
bar=donor   line=cohort median 		15.3 15.5 80.5%
3 IL1B 10.4
bar=donor   line=cohort median 		9.5 9.3 97.3%
4 CXCL8 11.6
bar=donor   line=cohort median 		10.6 11.4 58.2%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 6.2
bar=donor   line=cohort median 		6.0 6.1 58.2%
6 FCGR3B 15.5
bar=donor   line=cohort median 		14.6 14.7 96.2%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.6
bar=donor   line=cohort median 		14.3 14.3 70.1%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.2
bar=donor   line=cohort median 		10.2 10.4 28.1%
9 CD3E 11.8
bar=donor   line=cohort median 		11.9 12.0 19.9%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 10.7
bar=donor   line=cohort median 		11.0 10.9 23.8%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 12.3
bar=donor   line=cohort median 		11.7 11.7 82.6%
12 GNLY 12.5
bar=donor   line=cohort median 		12.0 12.1 78.7%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.2
bar=donor   line=cohort median 		16.4 16.4 13.1%
17 MT-CO2 15.1
bar=donor   line=cohort median 		15.2 15.3 27.1%
18 MT-ND1 14.8
bar=donor   line=cohort median 		15.0 15.2 9.1%
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