GSM8077599

Dataset: gse255685 • Sample: YZ835 • Status: MDD without drug therapy
◂ Prev All Donors Next ▸

Quality Control Metrics

2 Mean expression score Group median: 2 • 29.6%ile (≈ Median)
22,358 Genes with score > 0 Group median: 22,375 • 24.6%ile (↓ Low)
0 Median expression score Group median: 0 • 12.0%ile (↓ Low)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

57.6Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 2.09
bar=donor   line=cohort median 		2.02 61.8%
FOXO3 Insulin/IGF-1 Signaling 10.05
bar=donor   line=cohort median 		9.99 57.5%
CETP Lipid Metabolism 4.78
bar=donor   line=cohort median 		5.05 18.8%
SIRT6 Sirtuin Family 8.41
bar=donor   line=cohort median 		8.34 64.0%
SIRT1 Sirtuin Family 8.87
bar=donor   line=cohort median 		8.72 79.4%
SIRT3 Sirtuin Family 7.19
bar=donor   line=cohort median 		7.49 7.0%
IGF1R Insulin/IGF-1 Signaling 10.38
bar=donor   line=cohort median 		10.21 70.1%
KLOTHO Anti-aging 2.98
bar=donor   line=cohort median 		2.51 95.5%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 37.5%
IL6 Inflammation 1.08
bar=donor   line=cohort median 		1.16 28.1%
TERT Telomere Maintenance 1.72
bar=donor   line=cohort median 		1.51 84.8%
IRS2 Insulin/IGF-1 Signaling 9.99
bar=donor   line=cohort median 		9.81 63.3%
TP53 Tumor Suppression 8.78
bar=donor   line=cohort median 		8.92 36.0%
SHC1 Signal Transduction 9.42
bar=donor   line=cohort median 		9.35 71.2%
ACE Signal Transduction 5.07
bar=donor   line=cohort median 		4.64 88.4%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.5 0
2 B2M 17.0 0
3 EEF1A1 16.7 0
4 ACTB 16.6 0
5 MT-CO1 16.5 0
6 HLA-C 16.4 0
7 MT-RNR1 16.1 0
8 HLA-B 16.0 0
9 FTL 15.9 0
10 HLA-E 15.8 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 14.4
bar=donor   line=cohort median 		13.8 14.2 63.6%
2 S100A9 15.8
bar=donor   line=cohort median 		15.3 15.5 70.4%
3 IL1B 9.5
bar=donor   line=cohort median 		9.5 9.3 59.3%
4 CXCL8 11.8
bar=donor   line=cohort median 		10.6 11.4 62.2%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 7.2
bar=donor   line=cohort median 		6.0 6.1 91.2%
6 FCGR3B 15.4
bar=donor   line=cohort median 		14.6 14.7 95.2%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 13.9
bar=donor   line=cohort median 		14.3 14.3 14.5%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.4
bar=donor   line=cohort median 		10.2 10.4 57.9%
9 CD3E 12.0
bar=donor   line=cohort median 		11.9 12.0 46.8%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 11.2
bar=donor   line=cohort median 		11.0 10.9 78.3%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 11.7
bar=donor   line=cohort median 		11.7 11.7 52.5%
12 GNLY 12.3
bar=donor   line=cohort median 		12.0 12.1 63.6%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.5
bar=donor   line=cohort median 		16.4 16.4 65.8%
17 MT-CO2 15.3
bar=donor   line=cohort median 		15.2 15.3 43.5%
18 MT-ND1 15.1
bar=donor   line=cohort median 		15.0 15.2 33.5%
◂ Previous Donor Back to Donor List Next Donor ▸