GSM8077601

Dataset: gse255685 • Sample: YZ840 • Status: MDD with drug therapy
◂ Prev All Donors Next ▸

Quality Control Metrics

2 Mean expression score Group median: 2 • 20.3%ile (↓ Low)
22,329 Genes with score > 0 Group median: 22,378 • 4.8%ile (↓ Low)
0 Median expression score Group median: 0 • 9.5%ile (↓ Low)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

44.3Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 1.95
bar=donor   line=cohort median 		2.02 40.0%
FOXO3 Insulin/IGF-1 Signaling 10.00
bar=donor   line=cohort median 		9.99 52.2%
CETP Lipid Metabolism 5.31
bar=donor   line=cohort median 		5.05 80.5%
SIRT6 Sirtuin Family 8.31
bar=donor   line=cohort median 		8.34 41.8%
SIRT1 Sirtuin Family 8.86
bar=donor   line=cohort median 		8.72 76.5%
SIRT3 Sirtuin Family 7.25
bar=donor   line=cohort median 		7.49 10.9%
IGF1R Insulin/IGF-1 Signaling 10.54
bar=donor   line=cohort median 		10.21 85.5%
KLOTHO Anti-aging 2.42
bar=donor   line=cohort median 		2.51 38.5%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 7.7%
IL6 Inflammation 0.98
bar=donor   line=cohort median 		1.16 2.3%
TERT Telomere Maintenance 1.40
bar=donor   line=cohort median 		1.51 24.9%
IRS2 Insulin/IGF-1 Signaling 9.75
bar=donor   line=cohort median 		9.81 43.2%
TP53 Tumor Suppression 9.02
bar=donor   line=cohort median 		8.92 68.3%
SHC1 Signal Transduction 9.30
bar=donor   line=cohort median 		9.35 31.7%
ACE Signal Transduction 4.73
bar=donor   line=cohort median 		4.64 60.0%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MTCO2P12 25.1 0
2 MT-RNR2 17.3 0
3 B2M 16.9 0
4 ACTB 16.6 0
5 EEF1A1 16.5 0
6 MT-CO1 16.3 0
7 HLA-C 16.1 0
8 HLA-B 15.9 0
9 MT-RNR1 15.8 0
10 HLA-E 15.7 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 14.2
bar=donor   line=cohort median 		14.2 14.2 50.0%
2 S100A9 15.6
bar=donor   line=cohort median 		15.4 15.5 56.1%
3 IL1B 9.7
bar=donor   line=cohort median 		9.5 9.3 73.7%
4 CXCL8 9.7
bar=donor   line=cohort median 		10.3 11.4 23.5%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 8.4
bar=donor   line=cohort median 		6.1 6.1 98.7%
6 FCGR3B 14.8
bar=donor   line=cohort median 		14.7 14.7 59.0%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 15.0
bar=donor   line=cohort median 		14.4 14.3 94.4%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.2
bar=donor   line=cohort median 		10.3 10.4 29.9%
9 CD3E 11.8
bar=donor   line=cohort median 		11.9 12.0 15.6%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 11.0
bar=donor   line=cohort median 		10.9 10.9 63.3%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 11.6
bar=donor   line=cohort median 		11.5 11.7 43.2%
12 GNLY 11.7
bar=donor   line=cohort median 		12.0 12.1 18.5%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.3
bar=donor   line=cohort median 		16.4 16.4 33.5%
17 MT-CO2 15.1
bar=donor   line=cohort median 		15.3 15.3 18.5%
18 MT-ND1 14.9
bar=donor   line=cohort median 		15.2 15.2 15.6%
◂ Previous Donor Back to Donor List Next Donor ▸