GSM8077602

Dataset: gse255685 • Sample: YZ843 • Status: MDD with drug therapy
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Quality Control Metrics

2 Mean expression score Group median: 2 • 38.5%ile (≈ Median)
22,357 Genes with score > 0 Group median: 22,378 • 23.1%ile (↓ Low)
0 Median expression score Group median: 0 • 12.7%ile (↓ Low)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

49.8Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 1.94
bar=donor   line=cohort median 		2.02 38.5%
FOXO3 Insulin/IGF-1 Signaling 9.66
bar=donor   line=cohort median 		9.99 11.3%
CETP Lipid Metabolism 5.03
bar=donor   line=cohort median 		5.05 47.1%
SIRT6 Sirtuin Family 8.33
bar=donor   line=cohort median 		8.34 48.9%
SIRT1 Sirtuin Family 8.77
bar=donor   line=cohort median 		8.72 61.8%
SIRT3 Sirtuin Family 7.63
bar=donor   line=cohort median 		7.49 74.7%
IGF1R Insulin/IGF-1 Signaling 10.21
bar=donor   line=cohort median 		10.21 50.7%
KLOTHO Anti-aging 2.32
bar=donor   line=cohort median 		2.51 20.3%
APOC3 Lipid Metabolism -2.10
bar=donor   line=cohort median 		-2.11 79.4%
IL6 Inflammation 1.22
bar=donor   line=cohort median 		1.16 63.3%
TERT Telomere Maintenance 1.60
bar=donor   line=cohort median 		1.51 70.8%
IRS2 Insulin/IGF-1 Signaling 9.34
bar=donor   line=cohort median 		9.81 10.9%
TP53 Tumor Suppression 9.11
bar=donor   line=cohort median 		8.92 81.2%
SHC1 Signal Transduction 9.29
bar=donor   line=cohort median 		9.35 28.5%
ACE Signal Transduction 4.73
bar=donor   line=cohort median 		4.64 59.7%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.9 0
2 B2M 16.9 0
3 EEF1A1 16.9 0
4 ACTB 16.5 0
5 MT-CO1 16.5 0
6 MT-RNR1 16.4 0
7 HLA-B 16.0 0
8 FTL 15.8 0
9 MT-ND4 15.7 0
10 HLA-E 15.7 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 13.7
bar=donor   line=cohort median 		14.2 14.2 23.5%
2 S100A9 15.2
bar=donor   line=cohort median 		15.4 15.5 23.5%
3 IL1B 9.4
bar=donor   line=cohort median 		9.5 9.3 55.7%
4 CXCL8 9.1
bar=donor   line=cohort median 		10.3 11.4 12.7%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 6.2
bar=donor   line=cohort median 		6.1 6.1 61.1%
6 FCGR3B 14.5
bar=donor   line=cohort median 		14.7 14.7 32.8%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 13.7
bar=donor   line=cohort median 		14.4 14.3 5.6%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.6
bar=donor   line=cohort median 		10.3 10.4 74.0%
9 CD3E 12.0
bar=donor   line=cohort median 		11.9 12.0 61.8%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 11.4
bar=donor   line=cohort median 		10.9 10.9 94.4%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 12.0
bar=donor   line=cohort median 		11.5 11.7 67.9%
12 GNLY 12.4
bar=donor   line=cohort median 		12.0 12.1 69.0%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.5
bar=donor   line=cohort median 		16.4 16.4 73.7%
17 MT-CO2 15.3
bar=donor   line=cohort median 		15.3 15.3 52.9%
18 MT-ND1 15.2
bar=donor   line=cohort median 		15.2 15.2 53.6%
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