GSM8077604

Dataset: gse255685 • Sample: YZ846 • Status: MDD without drug therapy
◂ Prev All Donors Next ▸

Quality Control Metrics

2 Mean expression score Group median: 2 • 60.0%ile (≈ Median)
22,364 Genes with score > 0 Group median: 22,375 • 31.7%ile (≈ Median)
0 Median expression score Group median: 0 • 64.3%ile (≈ Median)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

51.3Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 1.73
bar=donor   line=cohort median 		2.02 5.9%
FOXO3 Insulin/IGF-1 Signaling 9.98
bar=donor   line=cohort median 		9.99 47.9%
CETP Lipid Metabolism 5.36
bar=donor   line=cohort median 		5.05 83.7%
SIRT6 Sirtuin Family 8.32
bar=donor   line=cohort median 		8.34 43.6%
SIRT1 Sirtuin Family 8.80
bar=donor   line=cohort median 		8.72 66.5%
SIRT3 Sirtuin Family 7.62
bar=donor   line=cohort median 		7.49 74.0%
IGF1R Insulin/IGF-1 Signaling 10.10
bar=donor   line=cohort median 		10.21 38.9%
KLOTHO Anti-aging 2.52
bar=donor   line=cohort median 		2.51 52.5%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 70.1%
IL6 Inflammation 1.01
bar=donor   line=cohort median 		1.16 14.2%
TERT Telomere Maintenance 1.49
bar=donor   line=cohort median 		1.51 45.0%
IRS2 Insulin/IGF-1 Signaling 9.25
bar=donor   line=cohort median 		9.81 7.4%
TP53 Tumor Suppression 9.19
bar=donor   line=cohort median 		8.92 91.9%
SHC1 Signal Transduction 9.34
bar=donor   line=cohort median 		9.35 47.9%
ACE Signal Transduction 4.96
bar=donor   line=cohort median 		4.64 80.5%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.7 0
2 B2M 16.8 0
3 EEF1A1 16.7 0
4 MT-CO1 16.5 0
5 ACTB 16.4 0
6 MT-RNR1 16.0 0
7 HLA-C 16.0 0
8 FKBP8 15.9 0
9 FTL 15.9 0
10 HLA-E 15.6 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 13.7
bar=donor   line=cohort median 		13.8 14.2 20.6%
2 S100A9 15.1
bar=donor   line=cohort median 		15.3 15.5 18.8%
3 IL1B 9.2
bar=donor   line=cohort median 		9.5 9.3 45.3%
4 CXCL8 8.8
bar=donor   line=cohort median 		10.6 11.4 8.8%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 5.9
bar=donor   line=cohort median 		6.0 6.1 35.7%
6 FCGR3B 14.4
bar=donor   line=cohort median 		14.6 14.7 27.1%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.1
bar=donor   line=cohort median 		14.3 14.3 33.9%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.5
bar=donor   line=cohort median 		10.2 10.4 65.1%
9 CD3E 12.1
bar=donor   line=cohort median 		11.9 12.0 64.7%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 11.1
bar=donor   line=cohort median 		11.0 10.9 69.4%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 12.1
bar=donor   line=cohort median 		11.7 11.7 73.3%
12 GNLY 12.4
bar=donor   line=cohort median 		12.0 12.1 67.6%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.5
bar=donor   line=cohort median 		16.4 16.4 56.1%
17 MT-CO2 15.1
bar=donor   line=cohort median 		15.2 15.3 28.5%
18 MT-ND1 15.1
bar=donor   line=cohort median 		15.0 15.2 32.4%
◂ Previous Donor Back to Donor List Next Donor ▸