GSM8077608

Dataset: gse255685 • Sample: YZ856 • Status: MDD without drug therapy
◂ Prev All Donors Next ▸

Quality Control Metrics

2 Mean expression score Group median: 2 • 88.7%ile (↑ High)
22,435 Genes with score > 0 Group median: 22,375 • 94.4%ile (↑ High)
0 Median expression score Group median: 0 • 89.8%ile (↑ High)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

57.9Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 1.79
bar=donor   line=cohort median 		2.02 11.7%
FOXO3 Insulin/IGF-1 Signaling 10.04
bar=donor   line=cohort median 		9.99 56.5%
CETP Lipid Metabolism 5.07
bar=donor   line=cohort median 		5.05 53.2%
SIRT6 Sirtuin Family 8.34
bar=donor   line=cohort median 		8.34 50.4%
SIRT1 Sirtuin Family 8.79
bar=donor   line=cohort median 		8.72 65.4%
SIRT3 Sirtuin Family 7.49
bar=donor   line=cohort median 		7.49 50.0%
IGF1R Insulin/IGF-1 Signaling 10.64
bar=donor   line=cohort median 		10.21 91.2%
KLOTHO Anti-aging 2.45
bar=donor   line=cohort median 		2.51 42.5%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 36.4%
IL6 Inflammation 1.16
bar=donor   line=cohort median 		1.16 50.7%
TERT Telomere Maintenance 1.59
bar=donor   line=cohort median 		1.51 69.0%
IRS2 Insulin/IGF-1 Signaling 10.05
bar=donor   line=cohort median 		9.81 66.5%
TP53 Tumor Suppression 8.87
bar=donor   line=cohort median 		8.92 46.4%
SHC1 Signal Transduction 9.49
bar=donor   line=cohort median 		9.35 84.1%
ACE Signal Transduction 5.22
bar=donor   line=cohort median 		4.64 94.8%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MTCO2P12 48.0 0
2 MT-RNR2 17.5 0
3 B2M 16.7 0
4 EEF1A1 16.6 0
5 ACTB 16.5 0
6 MT-CO1 16.5 0
7 MT-RNR1 15.9 0
8 MT-ND4 15.7 0
9 HLA-B 15.7 0
10 HLA-E 15.6 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 14.0
bar=donor   line=cohort median 		13.8 14.2 38.2%
2 S100A9 15.5
bar=donor   line=cohort median 		15.3 15.5 45.7%
3 IL1B 9.4
bar=donor   line=cohort median 		9.5 9.3 53.2%
4 CXCL8 12.0
bar=donor   line=cohort median 		10.6 11.4 67.6%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 7.4
bar=donor   line=cohort median 		6.0 6.1 92.7%
6 FCGR3B 14.5
bar=donor   line=cohort median 		14.6 14.7 34.2%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.9
bar=donor   line=cohort median 		14.3 14.3 90.5%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.0
bar=donor   line=cohort median 		10.2 10.4 14.9%
9 CD3E 11.7
bar=donor   line=cohort median 		11.9 12.0 8.1%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 11.2
bar=donor   line=cohort median 		11.0 10.9 82.6%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 11.4
bar=donor   line=cohort median 		11.7 11.7 21.3%
12 GNLY 11.7
bar=donor   line=cohort median 		12.0 12.1 18.1%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.5
bar=donor   line=cohort median 		16.4 16.4 70.4%
17 MT-CO2 15.3
bar=donor   line=cohort median 		15.2 15.3 40.7%
18 MT-ND1 15.3
bar=donor   line=cohort median 		15.0 15.2 60.8%
◂ Previous Donor Back to Donor List Next Donor ▸