GSM8077612

Dataset: gse255685 • Sample: YZ894 • Status: MDD with drug therapy
◂ Prev All Donors Next ▸

Quality Control Metrics

2 Mean expression score Group median: 2 • 7.3%ile (↓ Low)
22,384 Genes with score > 0 Group median: 22,378 • 59.9%ile (≈ Median)
0 Median expression score Group median: 0 • 48.6%ile (≈ Median)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

51.5Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 1.86
bar=donor   line=cohort median 		2.02 23.5%
FOXO3 Insulin/IGF-1 Signaling 9.74
bar=donor   line=cohort median 		9.99 18.5%
CETP Lipid Metabolism 5.59
bar=donor   line=cohort median 		5.05 94.4%
SIRT6 Sirtuin Family 8.41
bar=donor   line=cohort median 		8.34 64.3%
SIRT1 Sirtuin Family 8.63
bar=donor   line=cohort median 		8.72 39.6%
SIRT3 Sirtuin Family 7.62
bar=donor   line=cohort median 		7.49 73.7%
IGF1R Insulin/IGF-1 Signaling 10.28
bar=donor   line=cohort median 		10.21 57.2%
KLOTHO Anti-aging 2.60
bar=donor   line=cohort median 		2.51 64.0%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 28.9%
IL6 Inflammation 1.15
bar=donor   line=cohort median 		1.16 49.3%
TERT Telomere Maintenance 1.44
bar=donor   line=cohort median 		1.51 33.2%
IRS2 Insulin/IGF-1 Signaling 9.36
bar=donor   line=cohort median 		9.81 13.4%
TP53 Tumor Suppression 9.20
bar=donor   line=cohort median 		8.92 93.0%
SHC1 Signal Transduction 9.59
bar=donor   line=cohort median 		9.35 93.0%
ACE Signal Transduction 4.39
bar=donor   line=cohort median 		4.64 26.7%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 ACTB 16.6 0
2 MT-CO1 16.3 0
3 MT-RNR2 16.2 0
4 EEF1A1 16.2 0
5 HLA-C 16.2 0
6 B2M 16.1 0
7 HLA-E 15.9 0
8 HLA-B 15.9 0
9 FKBP8 15.8 0
10 FTL 15.6 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 12.4
bar=donor   line=cohort median 		14.2 14.2 3.8%
2 S100A9 14.8
bar=donor   line=cohort median 		15.4 15.5 5.6%
3 IL1B 9.6
bar=donor   line=cohort median 		9.5 9.3 66.8%
4 CXCL8 8.4
bar=donor   line=cohort median 		10.3 11.4 3.0%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 5.7
bar=donor   line=cohort median 		6.1 6.1 15.2%
6 FCGR3B 14.7
bar=donor   line=cohort median 		14.7 14.7 52.9%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.6
bar=donor   line=cohort median 		14.4 14.3 76.2%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 9.7
bar=donor   line=cohort median 		10.3 10.4 4.1%
9 CD3E 12.1
bar=donor   line=cohort median 		11.9 12.0 75.4%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 10.8
bar=donor   line=cohort median 		10.9 10.9 39.6%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 11.6
bar=donor   line=cohort median 		11.5 11.7 45.7%
12 GNLY 11.9
bar=donor   line=cohort median 		12.0 12.1 29.6%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.3
bar=donor   line=cohort median 		16.4 16.4 19.2%
17 MT-CO2 15.1
bar=donor   line=cohort median 		15.3 15.3 23.5%
18 MT-ND1 14.9
bar=donor   line=cohort median 		15.2 15.2 14.9%
◂ Previous Donor Back to Donor List Next Donor ▸