GSM8077613

Dataset: gse255685 • Sample: YZ897 • Status: MDD without drug therapy
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Quality Control Metrics

2 Mean expression score Group median: 2 • 7.0%ile (↓ Low)
22,370 Genes with score > 0 Group median: 22,375 • 38.9%ile (≈ Median)
0 Median expression score Group median: 0 • 48.2%ile (≈ Median)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

51.1Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 1.67
bar=donor   line=cohort median 		2.02 0.2%
FOXO3 Insulin/IGF-1 Signaling 9.99
bar=donor   line=cohort median 		9.99 48.9%
CETP Lipid Metabolism 5.05
bar=donor   line=cohort median 		5.05 50.0%
SIRT6 Sirtuin Family 8.46
bar=donor   line=cohort median 		8.34 72.2%
SIRT1 Sirtuin Family 8.74
bar=donor   line=cohort median 		8.72 53.6%
SIRT3 Sirtuin Family 7.57
bar=donor   line=cohort median 		7.49 65.1%
IGF1R Insulin/IGF-1 Signaling 10.30
bar=donor   line=cohort median 		10.21 58.6%
KLOTHO Anti-aging 2.56
bar=donor   line=cohort median 		2.51 57.9%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 4.8%
IL6 Inflammation 1.25
bar=donor   line=cohort median 		1.16 67.2%
TERT Telomere Maintenance 1.33
bar=donor   line=cohort median 		1.51 12.0%
IRS2 Insulin/IGF-1 Signaling 9.64
bar=donor   line=cohort median 		9.81 32.8%
TP53 Tumor Suppression 9.34
bar=donor   line=cohort median 		8.92 97.7%
SHC1 Signal Transduction 9.60
bar=donor   line=cohort median 		9.35 93.4%
ACE Signal Transduction 4.67
bar=donor   line=cohort median 		4.64 51.4%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 ACTB 16.7 0
2 B2M 16.4 0
3 EEF1A1 16.4 0
4 MT-CO1 16.3 0
5 MT-RNR2 16.2 0
6 HLA-C 16.1 0
7 HLA-E 15.8 0
8 CSF3R 15.8 0
9 HLA-B 15.5 0
10 TXNIP 15.4 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 13.1
bar=donor   line=cohort median 		13.8 14.2 10.2%
2 S100A9 14.9
bar=donor   line=cohort median 		15.3 15.5 10.9%
3 IL1B 9.6
bar=donor   line=cohort median 		9.5 9.3 66.1%
4 CXCL8 8.8
bar=donor   line=cohort median 		10.6 11.4 9.5%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 6.7
bar=donor   line=cohort median 		6.0 6.1 80.5%
6 FCGR3B 14.7
bar=donor   line=cohort median 		14.6 14.7 52.2%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.9
bar=donor   line=cohort median 		14.3 14.3 87.6%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 9.9
bar=donor   line=cohort median 		10.2 10.4 7.7%
9 CD3E 11.9
bar=donor   line=cohort median 		11.9 12.0 44.3%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 10.9
bar=donor   line=cohort median 		11.0 10.9 47.5%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 11.7
bar=donor   line=cohort median 		11.7 11.7 48.9%
12 GNLY 11.9
bar=donor   line=cohort median 		12.0 12.1 32.1%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.3
bar=donor   line=cohort median 		16.4 16.4 14.9%
17 MT-CO2 14.7
bar=donor   line=cohort median 		15.2 15.3 1.6%
18 MT-ND1 14.7
bar=donor   line=cohort median 		15.0 15.2 5.6%
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