GSM8077617

Dataset: gse255685 • Sample: YZ936 • Status: MDD with drug therapy
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Quality Control Metrics

2 Mean expression score Group median: 2 • 1.6%ile (↓ Low)
22,335 Genes with score > 0 Group median: 22,378 • 7.3%ile (↓ Low)
0 Median expression score Group median: 0 • 11.3%ile (↓ Low)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

56.3Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 1.91
bar=donor   line=cohort median 		2.02 33.9%
FOXO3 Insulin/IGF-1 Signaling 9.75
bar=donor   line=cohort median 		9.99 20.6%
CETP Lipid Metabolism 5.07
bar=donor   line=cohort median 		5.05 52.5%
SIRT6 Sirtuin Family 8.58
bar=donor   line=cohort median 		8.34 85.1%
SIRT1 Sirtuin Family 8.54
bar=donor   line=cohort median 		8.72 24.2%
SIRT3 Sirtuin Family 7.80
bar=donor   line=cohort median 		7.49 94.8%
IGF1R Insulin/IGF-1 Signaling 10.34
bar=donor   line=cohort median 		10.21 65.8%
KLOTHO Anti-aging 2.90
bar=donor   line=cohort median 		2.51 91.6%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 12.7%
IL6 Inflammation 0.98
bar=donor   line=cohort median 		1.16 2.7%
TERT Telomere Maintenance 1.55
bar=donor   line=cohort median 		1.51 59.0%
IRS2 Insulin/IGF-1 Signaling 9.47
bar=donor   line=cohort median 		9.81 19.9%
TP53 Tumor Suppression 9.41
bar=donor   line=cohort median 		8.92 98.8%
SHC1 Signal Transduction 9.62
bar=donor   line=cohort median 		9.35 94.8%
ACE Signal Transduction 5.06
bar=donor   line=cohort median 		4.64 87.6%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MTCO2P12 24.7 0
2 MT-CO1 16.7 0
3 ACTB 16.6 0
4 MT-RNR2 16.4 0
5 HLA-C 16.3 0
6 EEF1A1 16.1 0
7 HLA-B 16.0 0
8 HLA-E 15.9 0
9 B2M 15.9 0
10 CSF3R 15.9 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 12.0
bar=donor   line=cohort median 		14.2 14.2 0.5%
2 S100A9 14.5
bar=donor   line=cohort median 		15.4 15.5 2.0%
3 IL1B 9.5
bar=donor   line=cohort median 		9.5 9.3 63.3%
4 CXCL8 8.6
bar=donor   line=cohort median 		10.3 11.4 5.9%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 6.0
bar=donor   line=cohort median 		6.1 6.1 43.5%
6 FCGR3B 15.0
bar=donor   line=cohort median 		14.7 14.7 72.9%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.8
bar=donor   line=cohort median 		14.4 14.3 86.2%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 9.8
bar=donor   line=cohort median 		10.3 10.4 5.9%
9 CD3E 12.2
bar=donor   line=cohort median 		11.9 12.0 85.1%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 10.7
bar=donor   line=cohort median 		10.9 10.9 26.3%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 11.7
bar=donor   line=cohort median 		11.5 11.7 48.6%
12 GNLY 12.0
bar=donor   line=cohort median 		12.0 12.1 42.1%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.7
bar=donor   line=cohort median 		16.4 16.4 91.9%
17 MT-CO2 15.2
bar=donor   line=cohort median 		15.3 15.3 35.3%
18 MT-ND1 15.3
bar=donor   line=cohort median 		15.2 15.2 68.6%
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