GSM8077619

Dataset: gse255685 • Sample: YZ942 • Status: MDD without drug therapy
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Quality Control Metrics

2 Mean expression score Group median: 2 • 6.6%ile (↓ Low)
22,365 Genes with score > 0 Group median: 22,375 • 32.8%ile (≈ Median)
0 Median expression score Group median: 0 • 63.6%ile (≈ Median)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

62.8Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 2.17
bar=donor   line=cohort median 		2.02 73.7%
FOXO3 Insulin/IGF-1 Signaling 10.13
bar=donor   line=cohort median 		9.99 74.7%
CETP Lipid Metabolism 5.56
bar=donor   line=cohort median 		5.05 93.0%
SIRT6 Sirtuin Family 8.56
bar=donor   line=cohort median 		8.34 83.7%
SIRT1 Sirtuin Family 8.54
bar=donor   line=cohort median 		8.72 24.6%
SIRT3 Sirtuin Family 7.84
bar=donor   line=cohort median 		7.49 97.3%
IGF1R Insulin/IGF-1 Signaling 10.44
bar=donor   line=cohort median 		10.21 75.1%
KLOTHO Anti-aging 2.81
bar=donor   line=cohort median 		2.51 86.9%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 6.6%
IL6 Inflammation 0.97
bar=donor   line=cohort median 		1.16 2.0%
TERT Telomere Maintenance 1.59
bar=donor   line=cohort median 		1.51 67.6%
IRS2 Insulin/IGF-1 Signaling 9.80
bar=donor   line=cohort median 		9.81 48.9%
TP53 Tumor Suppression 9.45
bar=donor   line=cohort median 		8.92 99.5%
SHC1 Signal Transduction 9.61
bar=donor   line=cohort median 		9.35 94.1%
ACE Signal Transduction 4.27
bar=donor   line=cohort median 		4.64 14.5%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 ACTB 16.7 0
2 MT-CO1 16.5 0
3 CSF3R 16.2 0
4 HLA-C 16.2 0
5 EEF1A1 16.1 0
6 MT-RNR2 16.1 0
7 HLA-E 15.9 0
8 HLA-B 15.9 0
9 B2M 15.8 0
10 CD74 15.5 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 12.3
bar=donor   line=cohort median 		13.8 14.2 3.4%
2 S100A9 14.8
bar=donor   line=cohort median 		15.3 15.5 7.3%
3 IL1B 9.9
bar=donor   line=cohort median 		9.5 9.3 84.8%
4 CXCL8 8.3
bar=donor   line=cohort median 		10.6 11.4 2.3%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 6.7
bar=donor   line=cohort median 		6.0 6.1 79.0%
6 FCGR3B 14.9
bar=donor   line=cohort median 		14.6 14.7 66.5%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.5
bar=donor   line=cohort median 		14.3 14.3 57.5%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 9.5
bar=donor   line=cohort median 		10.2 10.4 1.6%
9 CD3E 12.1
bar=donor   line=cohort median 		11.9 12.0 72.2%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 11.1
bar=donor   line=cohort median 		11.0 10.9 69.7%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 10.9
bar=donor   line=cohort median 		11.7 11.7 1.6%
12 GNLY 11.5
bar=donor   line=cohort median 		12.0 12.1 9.1%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.5
bar=donor   line=cohort median 		16.4 16.4 65.4%
17 MT-CO2 14.9
bar=donor   line=cohort median 		15.2 15.3 5.2%
18 MT-ND1 14.6
bar=donor   line=cohort median 		15.0 15.2 2.7%
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