GSM8077621

Dataset: gse255685 • Sample: YZ948 • Status: MDD with drug therapy
◂ Prev All Donors Next ▸

Quality Control Metrics

2 Mean expression score Group median: 2 • 23.5%ile (↓ Low)
22,364 Genes with score > 0 Group median: 22,378 • 31.7%ile (≈ Median)
0 Median expression score Group median: 0 • 36.7%ile (≈ Median)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

64.8Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 1.76
bar=donor   line=cohort median 		2.02 8.1%
FOXO3 Insulin/IGF-1 Signaling 10.19
bar=donor   line=cohort median 		9.99 82.6%
CETP Lipid Metabolism 5.93
bar=donor   line=cohort median 		5.05 98.8%
SIRT6 Sirtuin Family 8.59
bar=donor   line=cohort median 		8.34 86.2%
SIRT1 Sirtuin Family 8.53
bar=donor   line=cohort median 		8.72 23.1%
SIRT3 Sirtuin Family 7.73
bar=donor   line=cohort median 		7.49 88.0%
IGF1R Insulin/IGF-1 Signaling 10.67
bar=donor   line=cohort median 		10.21 93.7%
KLOTHO Anti-aging 3.00
bar=donor   line=cohort median 		2.51 96.2%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 10.6%
IL6 Inflammation 1.13
bar=donor   line=cohort median 		1.16 41.0%
TERT Telomere Maintenance 1.41
bar=donor   line=cohort median 		1.51 26.3%
IRS2 Insulin/IGF-1 Signaling 9.91
bar=donor   line=cohort median 		9.81 58.2%
TP53 Tumor Suppression 9.14
bar=donor   line=cohort median 		8.92 85.1%
SHC1 Signal Transduction 9.69
bar=donor   line=cohort median 		9.35 98.0%
ACE Signal Transduction 4.88
bar=donor   line=cohort median 		4.64 75.5%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 ACTB 16.7 0
2 CSF3R 16.5 0
3 HLA-C 16.5 0
4 HLA-E 16.1 0
5 MT-CO1 16.1 0
6 B2M 16.0 0
7 MT-RNR2 15.9 0
8 HLA-B 15.9 0
9 EEF1A1 15.8 0
10 TXNIP 15.7 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 12.2
bar=donor   line=cohort median 		14.2 14.2 1.6%
2 S100A9 14.8
bar=donor   line=cohort median 		15.4 15.5 7.0%
3 IL1B 9.7
bar=donor   line=cohort median 		9.5 9.3 74.0%
4 CXCL8 8.6
bar=donor   line=cohort median 		10.3 11.4 7.0%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 5.8
bar=donor   line=cohort median 		6.1 6.1 27.8%
6 FCGR3B 15.1
bar=donor   line=cohort median 		14.7 14.7 81.5%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.7
bar=donor   line=cohort median 		14.4 14.3 80.8%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 9.3
bar=donor   line=cohort median 		10.3 10.4 0.2%
9 CD3E 11.8
bar=donor   line=cohort median 		11.9 12.0 17.7%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 10.6
bar=donor   line=cohort median 		10.9 10.9 22.8%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 11.7
bar=donor   line=cohort median 		11.5 11.7 52.9%
12 GNLY 12.0
bar=donor   line=cohort median 		12.0 12.1 40.7%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.1
bar=donor   line=cohort median 		16.4 16.4 2.0%
17 MT-CO2 14.7
bar=donor   line=cohort median 		15.3 15.3 2.0%
18 MT-ND1 14.7
bar=donor   line=cohort median 		15.2 15.2 3.8%
◂ Previous Donor Back to Donor List Next Donor ▸