GSM8077622

Dataset: gse255685 • Sample: YZ949 • Status: MDD with drug therapy
◂ Prev All Donors Next ▸

Quality Control Metrics

2 Mean expression score Group median: 2 • 2.7%ile (↓ Low)
22,378 Genes with score > 0 Group median: 22,378 • 50.0%ile (≈ Median)
0 Median expression score Group median: 0 • 60.8%ile (≈ Median)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

53.2Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 1.92
bar=donor   line=cohort median 		2.02 34.6%
FOXO3 Insulin/IGF-1 Signaling 9.92
bar=donor   line=cohort median 		9.99 42.1%
CETP Lipid Metabolism 5.36
bar=donor   line=cohort median 		5.05 84.4%
SIRT6 Sirtuin Family 8.30
bar=donor   line=cohort median 		8.34 39.3%
SIRT1 Sirtuin Family 8.63
bar=donor   line=cohort median 		8.72 39.3%
SIRT3 Sirtuin Family 7.75
bar=donor   line=cohort median 		7.49 90.9%
IGF1R Insulin/IGF-1 Signaling 10.50
bar=donor   line=cohort median 		10.21 82.6%
KLOTHO Anti-aging 2.56
bar=donor   line=cohort median 		2.51 58.2%
APOC3 Lipid Metabolism -2.12
bar=donor   line=cohort median 		-2.11 2.0%
IL6 Inflammation 0.97
bar=donor   line=cohort median 		1.16 0.2%
TERT Telomere Maintenance 1.70
bar=donor   line=cohort median 		1.51 84.1%
IRS2 Insulin/IGF-1 Signaling 9.59
bar=donor   line=cohort median 		9.81 28.5%
TP53 Tumor Suppression 9.16
bar=donor   line=cohort median 		8.92 88.7%
SHC1 Signal Transduction 9.52
bar=donor   line=cohort median 		9.35 89.1%
ACE Signal Transduction 4.47
bar=donor   line=cohort median 		4.64 34.2%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 ACTB 16.4 0
2 HLA-C 16.3 0
3 EEF1A1 16.3 0
4 B2M 16.1 0
5 MT-CO1 16.0 0
6 CSF3R 15.8 0
7 HLA-E 15.8 0
8 MT-RNR2 15.8 0
9 HLA-B 15.5 0
10 FKBP8 15.4 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 12.2
bar=donor   line=cohort median 		14.2 14.2 2.0%
2 S100A9 14.3
bar=donor   line=cohort median 		15.4 15.5 0.9%
3 IL1B 9.6
bar=donor   line=cohort median 		9.5 9.3 66.5%
4 CXCL8 8.5
bar=donor   line=cohort median 		10.3 11.4 4.8%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 5.4
bar=donor   line=cohort median 		6.1 6.1 3.4%
6 FCGR3B 14.7
bar=donor   line=cohort median 		14.7 14.7 56.8%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 13.8
bar=donor   line=cohort median 		14.4 14.3 9.5%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 9.9
bar=donor   line=cohort median 		10.3 10.4 7.3%
9 CD3E 12.3
bar=donor   line=cohort median 		11.9 12.0 86.9%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 10.8
bar=donor   line=cohort median 		10.9 10.9 32.1%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 11.9
bar=donor   line=cohort median 		11.5 11.7 61.8%
12 GNLY 12.3
bar=donor   line=cohort median 		12.0 12.1 65.1%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.0
bar=donor   line=cohort median 		16.4 16.4 1.6%
17 MT-CO2 14.6
bar=donor   line=cohort median 		15.3 15.3 0.5%
18 MT-ND1 14.3
bar=donor   line=cohort median 		15.2 15.2 0.5%
◂ Previous Donor Back to Donor List Next Donor ▸