GSM8077629

Dataset: gse255685 • Sample: Z291 • Status: Healthy control
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Quality Control Metrics

2 Mean expression score Group median: 2 • 0.2%ile (↓ Low)
22,297 Genes with score > 0 Group median: 22,381 • 0.2%ile (↓ Low)
0 Median expression score Group median: 0 • 0.2%ile (↓ Low)

GSE255685 provides per-sample processed expression-score files; values are not raw counts.

Longevity Gene Set (15)

36.3Longevity Score (mean cohort rank, 15/15 genes)
GenePathwayExpression (rlog)vs CohortCohort Median%ile
APOE Lipid Metabolism 1.87
bar=donor   line=cohort median 		2.02 25.6%
FOXO3 Insulin/IGF-1 Signaling 9.70
bar=donor   line=cohort median 		9.99 14.9%
CETP Lipid Metabolism 5.03
bar=donor   line=cohort median 		5.05 47.9%
SIRT6 Sirtuin Family 8.10
bar=donor   line=cohort median 		8.34 5.2%
SIRT1 Sirtuin Family 9.08
bar=donor   line=cohort median 		8.72 98.8%
SIRT3 Sirtuin Family 7.06
bar=donor   line=cohort median 		7.49 2.7%
IGF1R Insulin/IGF-1 Signaling 9.74
bar=donor   line=cohort median 		10.21 14.2%
KLOTHO Anti-aging 2.77
bar=donor   line=cohort median 		2.51 84.1%
APOC3 Lipid Metabolism -2.11
bar=donor   line=cohort median 		-2.11 37.8%
IL6 Inflammation 1.08
bar=donor   line=cohort median 		1.16 28.5%
TERT Telomere Maintenance 1.52
bar=donor   line=cohort median 		1.51 51.8%
IRS2 Insulin/IGF-1 Signaling 9.19
bar=donor   line=cohort median 		9.81 5.9%
TP53 Tumor Suppression 9.16
bar=donor   line=cohort median 		8.92 89.1%
SHC1 Signal Transduction 9.21
bar=donor   line=cohort median 		9.35 9.1%
ACE Signal Transduction 4.44
bar=donor   line=cohort median 		4.64 29.6%

Single Gene Lookup

- Expression: - Cohort median: - Cohort %ile: - -

Top 20 Expressed Genes

#GeneIDTypeExpression (Expression score)Count
1 MT-RNR2 17.6 0
2 B2M 17.3 0
3 EEF1A1 17.0 0
4 ACTB 16.6 0
5 MT-CO1 16.6 0
6 HLA-C 16.3 0
7 HLA-B 16.2 0
8 MT-RNR1 16.0 0
9 MT-ND4 15.9 0
10 HLA-E 15.8 0

Immune Marker Gene Expression (15 markers)

Inflammation / myeloid (4)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
1 S100A8 14.4
bar=donor   line=cohort median 		14.4 14.2 62.2%
2 S100A9 15.7
bar=donor   line=cohort median 		15.8 15.5 62.2%
3 IL1B 9.6
bar=donor   line=cohort median 		8.8 9.3 67.2%
4 CXCL8 10.9
bar=donor   line=cohort median 		12.2 11.4 40.7%

Neutrophil (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
5 MPO 5.7
bar=donor   line=cohort median 		6.1 6.1 16.7%
6 FCGR3B 15.0
bar=donor   line=cohort median 		14.7 14.7 74.4%

Myeloid (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
7 LYZ 14.9
bar=donor   line=cohort median 		14.3 14.3 86.9%

T cells (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
8 CD3D 10.8
bar=donor   line=cohort median 		10.6 10.4 91.2%
9 CD3E 12.4
bar=donor   line=cohort median 		12.1 12.0 93.7%

B cells (1)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
10 MS4A1 10.4
bar=donor   line=cohort median 		10.8 10.9 9.9%

NK / cytotoxic (2)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
11 NKG7 12.1
bar=donor   line=cohort median 		12.2 11.7 72.9%
12 GNLY 12.5
bar=donor   line=cohort median 		12.4 12.1 78.0%

Mitochondrial (3)

#GeneTypeExpressionvs CohortGroup MedianCohort Median%ile
16 MT-CO1 16.6
bar=donor   line=cohort median 		16.5 16.4 81.5%
17 MT-CO2 15.5
bar=donor   line=cohort median 		15.6 15.3 74.7%
18 MT-ND1 15.3
bar=donor   line=cohort median 		15.3 15.2 66.1%
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